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三氯苯达唑治疗人肝片形吸虫的临床疗效观察 被引量:14

On Clinical Manifestation and Therapeutic Effect of First Use of Triclabendazole Treatment of Fasciola
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摘要 目的:探讨肝片形吸虫感染的有效治疗方法。方法:对我院住院治疗的7例肝片形吸虫感染患者进行临床资料分析,研究其使用三氯苯达唑与其它抗寄生虫药物治疗的对比。结果:7例患者均有相同的临床表现,阿苯达唑、吡喹酮等药物治疗无效,三氯达苯唑有效。结论:通过这次肝片形吸虫感染的治疗和临床分析,三氯苯达唑是一种具有良好抗肝片形吸虫药效的药物,对今后治疗肝片形虫病有一定指导作用。 Objective: To explore the effective treatment of Fasciola hepatica infection.Methods: An analysis of the use of Triclabendazole treatment and other antiparasitic drugs in the clinical manifestations was made among 7 cases of Fasciola hepatica infection in patients with clinical data and treatment from our hospital,and the corresponding treatment programs were compared.Results: 7 patients had the same clinical manifestations,which were that Albendazole and Praziquantel drug therapy were ineffective,while Triclabendazole effective.Conclusion: Though the treatment of Fasciola hepatica infection,Triclabendazole,as a good drug of anti-Fasciola hepatica,has a role in guiding the future treatment of Fasciolasis hepatica.
出处 《大理学院学报(综合版)》 CAS 2012年第3期49-51,共3页 Journal of Dali University
关键词 肝片形吸虫 治疗 三氯苯达唑 疗效 Fasciola hepatica treatment Triclabendazole effect
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参考文献7

  • 1付歆颖,丁俊涛.肝片形吸虫导致胆道感染一例[J].中华肝胆外科杂志,2005,11(9):623-623. 被引量:13
  • 2Tanir G, Karaman A, Tufekcl SB, et al. A case of ectopic intraabdominal fascioliasis presented with acute abdomen [J].Turk J Gastroenterol. 2011, 22 ( 3 ) : 347-350.
  • 3Scarcella S, Lamenza P, Virkel G, et al. Expression differeniial of microsomal and cytosolic glutathione-S-transferases in Fasciola hepatica resistant at triclabendazole [J].Mol Biochem Parasitol. 2012,181 ( 1 ):37-9.
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  • 5刘明达,刘约翰.三氯苯达唑治疗卫氏并殖吸虫病的疗效观察[J].中国寄生虫病防治杂志,2005,18(4):318-318. 被引量:9
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二级参考文献3

  • 1Bray TO, Crowfoot PD, Strong MB, et al. Treatment of immature and mature fasoldae hepatica infection in sheep with tviclabenazole[J]. Vet Rec,1983,113:3l5-3l7.
  • 2Weben F, Bushmen E, Buttnen DW. The effect of tviclabendazole on the lung fluke paragonimus in the experimental host sigmoid mdus[J].Fop Med Parasite,1988,39:322.
  • 3胡鹏,刘约翰.三氯苯达唑治疗斯氏狸殖吸虫病的初步观察[J].中国寄生虫学与寄生虫病杂志,2001,19(5):305-307. 被引量:12

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