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吲哚胺2,3-二氧化酶的生物学性质及与疾病的关系 被引量:3

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摘要 吲哚胺2,3-二氧化酶(Indoleamine2,3-dioxygenase,IDO.INDO)是催化肝外色氨酸(Trp)及吲哚衍生物代谢的限速酶。γ-干扰素(IFN-γ)能够激活IDO,导致Trp缺乏,并生成多种具有生物活性的代谢产物。IDO在抗肿瘤、抗病原体及免疫排斥反应中有重要作用。
作者 王敏慧
出处 《国外医学(临床生物化学与检验学分册)》 2000年第3期151-153,共3页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
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同被引文献35

  • 1Rovers MM,Schilder AG,Zielhuis GA,Rosenfeld RM,张江平,杨妙丽,张全安.中耳炎[J].国外医学(耳鼻咽喉科学分册),2005,29(3):141-143. 被引量:442
  • 2王文军,李连宏,张众.胃癌免疫逃逸机制的研究进展[J].国外医学(肿瘤学分册),2005,32(7):545-548. 被引量:2
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