摘要
[目的]探讨心理干预对系统性红斑狼疮(SLE)病人身心症状的影响。[方法]检索PubMed、SCI、EBSCO、Co-chrane Library、中国生物医学文献数据库及数字化期刊全文数据库等资源,收集有关对比心理干预和常规护理对SLE病人身心症状影响的随机对照试验(RCTs)。采用Jadad等设计的质量评价标准评价纳入文献的质量,提取相关数据,采用RevMan 5.1软件进行统计分析。[结果]最终纳入6个RCTs,包括537例研究对象。质量评价结果显示,2个研究Jadad评分≥4分为高质量研究,其余研究质量较低。Meta分析结果显示,与常规护理相比,心理干预可有效减小SLE病人的心理压力(P<0.05),使其焦虑、抑郁情绪得到缓解(P<0.05),同时还可降低病人的疾病活动度(P<0.05)。[结论]心理干预是一种科学有效的辅助治疗方法,在SLE病人心理症状的改善和治疗效果的提高中发挥了积极作用;但研究纳入的RCTs数量较少且样本量小,未来应开展更多设计严谨的大样本试验予以验证,并应关注不同心理干预手段的应用效果。
Objective： To probe into the influence of psychological interventions on psychosomatic symptoms in patients with systemic lupus erythematosus （SLE）. Methods. The PubMed, SCI, EBSCO, the Cochrane Library,Chinese Biomedical Literature Database and digital journals fulltext database were retrieved and to collect the randomized controlled trial on influence of psychological intervention and routine nursing for psychosomatic symptoms of SLE patients. Using the quality evaluation criteria designed by Jadad to evaluate the quality of Included literatures,and collect related data,and using RevMan 5.1 software for statistical analysis. Results：Finally, six RCTs were involved and 537 patients were included. Quality evaluation results showed the Jadad score≥4 of two studies were highquality research, and the other studies were of lower quality. Results of Meta analysis showed compared with routine care, the psychological intervention can effectively reduce the psychological pressure of SLE patients （P^0. 05） ,and relieve the anxiety and depression（P（0. 05）, at the same time reduce the disease activity of patients （P〈0.05）. Conclusion：The psychological intervention is a scientific and effective adjuvant therapy,and it plays a positive role in the improvement of psychosomatic symptom and curative effect. However, because the number of RCTs was less and sample sizes was smaller,the findings should be further confirmed through rigorous largescale randomized controlled tri- als. In addition, further studies should pay attention to the effects of various psychological interventions.
出处
《护理研究（上旬版）》
2012年第5期1240-1243,共4页
Chinese Nursing Researsh
关键词
系统性红斑狼疮
心理干预
身心症状
系统评价
systemic lupus erythematosus
psychological intervention
psychosomatic symptom
systemic review
