摘要
目的:探讨血脂、血糖与脑卒中的病因学关系。方法:选择100例脑卒中患者(脑梗死59例、脑出血41例)作为观察组,选择100例无影响血脂代谢及神经系统疾病健康体检者作为对照组。分别将脑卒中、脑梗死、脑出血患者的总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL)、低密度脂蛋白胆固醇(LDL)、载脂蛋白A(ApoA)、载脂蛋白B(ApoB)水平与对照组患者进行比较。结果:脑卒中及脑出血患者TC、TG、HDL、LDL、ApoB与对照组比较差异有统计学意义(P<0.01),脑梗死患者TC、TG、HDL、LDL、ApoA、ApoB与对照组比较差异有统计学意义(P<0.01,P<0.05)。结论:血脂与脑血管病有一定关系,TG、HDL、LDL是预测脑卒中发病的重要易患因子;高血糖可能与严重脑卒中患者的预后有关。
Objective：To analyze the etiological relationship between blood lipid, blood glucose and stroke. Methods ：100 patients with stroke （59 patients with cerebral infarction,41 patients with cerebral hemorrhage） were taken as the observation group and other 100 healthy people without lipid metabolism disorder and nervous system disease were taken as the control group. The levels of total cholesterol （ TC）, triglyceride （ TG ）, high density lipoprotein cholesterol （ HDL ）, low density lipoprotein cholesterol （ LDL）, apolipoprotein A （ApoA） and apolipoprotein B （ ApoB） of patients with stroke, cerebral infarction and cerebral hemorrhage in the observation group were respectively compared with those of the control group. Results ： There were statistically significant differences in the comparison of TC, TG, HDL,LDL and ApoB of patients with stroke and cerebral hemorrhage and healthy people between the two groups （P 〈 0.01 ） ;the differences in the comparison of TC, TG HDL, LDL,ApoA and ApoB of patients with cerebral infarction and healthy people were statistically significant between the two groups （ P 〈 0. 01, P 〈 0.05 ）. Conclusion ： The blood lipid has certain connection with cerebrovascular diseases. TG, HDL, LDL is the predictor of risk factors of stroke onset;hyperglycemia may be associated with the prognosis of patients with severe stroke.
关键词
脑卒中
血脂
血糖
病因学分析
Stroke
Blood lipid
Blood glucose
Etiological analysis
