摘要
目的观察米索前列醇在足月妊娠促宫颈成熟和引产的临床疗效。方法选取2011年2月至2011年10月期间在我院产科住院因各种原因需行引产的足月妊娠孕妇72例作为观察对象,随机分为观察组及对照组各36例,对照组采取缩宫素引产,观察组使用米索前列醇引产,观察两组孕妇用药后临床疗效。结果两组孕妇用药到临床时间、用药到宫颈后开全时间、总产程比较观察组短于对照组,组间比较存在显著性差异(P<0.05);两组孕妇用药72h后引产效果比较,对照组总有效率80.56%,观察组总有效率100.00%,比较存在显著性差异(P<0.05);在胎儿宫内窘迫、剖宫产、产后2h出血量及新生儿Apgar 1分钟评分等方面比较,无显著性差异(P>0.05)。结论米索前列醇在足月妊娠中局部阴道放药能促进宫颈成熟,引产效果明显优于缩宫素引产,小剂量的用药安全。
Objective To observe curative effect of misoprostol in term pregnancy cervical ripening and odinopoeia.Methods Selected 72 cases of full-term pregnancy who need odinopoeia for various reasons during hospitalizationin in our hospital maternity.All patients were randomLy divided into two groups.The control group has 36 cases which applied uterine contraction odinopoeia.The observation group has 36 cases which applied misoprostol odinopoeia.Observe the curative effect in the two groups after the treatment.Results Time to clinical medication,treatment to cervical after full time,total labor of pregnancy in the observation group are shorter than control group.It is significantly different between the two groups（P 0.05）.Compared odinopoeia effect of pregnancy in the two groups 72h after using the medication.The total efficiency of the control group is 80.56%,and 100.00% in observation group.It is significantly different（P0.05）.There is no significant difference in trauterine fetal distress,cesarean section、postpartum hemorrhage volume 2h,neonatal apgar score of 1 minutes and some other sides（P0.05）.Conclusion Misoprostol topical vaginal medication in term pregnancy can promote cervical ripening.Its odinopoeia effect is significantly better than uterine contraction odinopoeia.It’s also safe for using in small dose.
出处
《中国医药指南》
2012年第12期19-20,共2页
Guide of China Medicine
关键词
米索前列醇
足月妊娠
宫颈成熟
引产
Misoprostol
Full-term pregnancy
Cervical ripening
Odinopoeia
