摘要
利用组合化学方法合成了一个含有60种不同结构的聚苯乙烯固载季铵盐相转移催化剂的催化剂库,以有外加碱条件下的亲核取代反应为探针反应,利用迭代法从中筛选出了活性最高的催化剂,建立了一种快速合成和筛选聚苯乙烯固载季铵盐相转移催化剂的方法。
A phase transfer catalyst (PTC) library of sixty different polystyrene - supported quaternary ammonium
salt catalysts was synthesized. The nucleophilic Substitution reaction under basic conditions was used as a probe reaction to identify the most active PTC in the library by using the iterative method, and a method of rapid synthesis and screening polystyrene - supported quaternary ammonium PTC was established.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2000年第2期224-227,共4页
Chinese Journal of Organic Chemistry
关键词
组合化学
相转移催化剂
聚苯乙烯
季铵盐
combinatorial chemistry method, 'mix and split' library procedure, iterative method, phase transfer catalysis, polymer - supported quaternary ammonium salt
