摘要
目的:分析肺炎支原体(MP)抗体阳性患儿的临床和实验室资料,为诊断和治疗肺炎支原体感染提供依据。方法:采用富士明胶颗粒凝集法,检测具有发热或呼吸道症状5～7天住院患儿的血清MP混合抗体,对其中807例MP抗体阳性患儿的临床资料进行分析。结果:5 405例患儿中MP抗体阳性率14.9%,2008～2010年MP抗体阳性率之间差异有统计学意义(P<0.05);女患儿MP抗体阳性率高于男患儿,差异有统计学意义(P<0.05);学龄前组MP感染率最高(P<0.05);2008年MP感染率没有明显的季节差异,2009年秋季MP感染率最高,2010年夏秋季节MP感染率高于春冬季节;807例MP抗体阳性患儿发生肺外合并症129例,占16.0%。结论:MP感染的好发人群有提前趋势,且在儿童中的感染呈逐年上升趋势;MP感染的季节性每年均有变化,MP感染肺外合并症多见。
Objective： To analyze the clinical and laboratory data of children with positive mycoplasma pneumoniae （MP） antibody, provide a basis for diagnosis and treatment of MP infection. Methods： Polystyrene latex agglutination reaction （PLA） was adopted to detect mixed serum MP antibodies of the hospitalized children with fever or symptoms of respiratory tract diseases, the clinical data of 807 children with positive MP antibody were analyzed. Results ： Among 5 405 children, the positive rate of MP antibody was 14. 9% , there was significant difference in the positive rate of MP antibody among 2008, 2009, and 2010 （ P 〈 0. 05 ） ; the positive rate of MP antibody in girls was significantly higher than that in boys, there was significant difference （P 〈 0. 05） ; the positive rate of MP antibody among the preschool children was the highest （ P 〈 0. 05 ） ; the positive rate of MP antibody had no obvious seasonal difference in 2008, while in 2009, the posi- tive rate of MP antibody in autumn was the highest; the positive rates of MP antibody in summer and autumn were higher than those in spring and winter in 2010. Among 807 children with positive MP antibody, 129 children were found with extrapulmonary complications, accounting for 16. 0%. Conclusion： The susceptible group of MP infection become younger, and the infection rate among children shows an increasing trend year by year; there is seasonal variation of MP infection every year, MP infection combined with extrapulmonary complications is common.
出处
《中国妇幼保健》
CAS
北大核心
2012年第16期2472-2474,共3页
Maternal and Child Health Care of China
关键词
肺炎支原体
抗体
儿童
Mycoplasma pneumoniae
Antibody
Children
