非小细胞肺癌患者血浆凝血酶激活的纤溶抑制物和组织因子途径抑制物及凝血酶原片段1+2的水平变化及临床意义
被引量:6
摘要
肿瘤导致的止凝血异常发生率较高,其病理生理变化主要为高凝状态或易栓症,临床表现为血栓形成和弥散性血管内凝血( disseminated intravascular coagulation, DIC )。
出处
《中华检验医学杂志》
CAS
CSCD
北大核心
2012年第5期466-468,共3页
Chinese Journal of Laboratory Medicine
基金
山东省自然科学基金资助项目(ZR2009CM083)
参考文献9
-
1徐成伟,王丽丽,吴晓本,赵敬杰,杜贻萌,姜翠英.冠状动脉粥样硬化性心脏病患者凝血酶激活的纤溶抑制物及其编码区基因多态性的研究[J].中华医学遗传学杂志,2008,25(4):438-442. 被引量:3
-
2徐成伟,吴晓本,许顺良,宁尚义,王泽筠.凝血酶激活的纤溶抑制物编码区基因多态性与脑梗塞亚型的关系[J].中华检验医学杂志,2009,32(6):685-688. 被引量:2
-
3李晓娜,丁进芳,王凤兰,钟兰君,李芳文,边玉军,张兴旺.凝血酶激活的纤溶抑制物与2型糖尿病微量白蛋白尿症的关系[J].中华检验医学杂志,2006,29(7):620-621. 被引量:2
-
4Hataji O, Taguchi O, Gabazza EC, et al. Increased circulating levels of thrombin-activatable fibrinolysis inhibitor in lung cancer patients. Am J Hematol,2004, 76:214-219.
-
5Koldas M, Gummus M, Seker M, et al. Thrombin-activatable fibrinolysis inhibitor levels in patients with non-small-cell lung cancer. Clin Lung Cancer,2008, 9 : 112-115.
-
6Donati MB. Thrombosis and cancer: Trousseau syndrome revisited. Best Pract Res Clin Haematol,2009 ,22 :3-8.
-
7Zacharski LR, Ornstein DL. Venous thromboembolism and cancer. N Engl J Med,2000,343 : 1338.
-
8Pavey S J, Hawson GA, Marsh NA. Impact of the fibrinolytic enzyme system on prognosis and survival associated with nonsmall cell lung carcinoma. Blood Coagul Fibfinolysis ,2001,12:51-58.
-
9Boffa MB, Koschinsky ML. Curiouser and curiouser: recent advances in measurement of thrombin-aetivatable fibrinolysis inhibitor (TAFI) and in understanding its molecular genetics, gene regulation, and biological roles. Clin Biochem, 2007, 40: 431-442.
二级参考文献28
-
1董宁征,吴成亮,季顺东,江淼,阮长耿.PAI-1和TAFIa对机体内源性纤溶的调控作用[J].江苏医药,2004,30(10):749-750. 被引量:5
-
2各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33093
-
3Bajzar L, Manuel R, Nesheim ME. Purification and characterization of TAFI, a thrombin-activatable fibrinolysis inhibitor. J Biol Chem, 1995, 270:14477-14484.
-
4VanhoofG, Wauters J, Schatteman K, et al. The gene for human carboxypeptidase U(cpu)-A proposed novel regulator of plasminogen activation-maps to 13q14.11. Genomics, 1996,38:454-455.
-
5Brouwers GJ, Vos HL, Leebeek FW, etal. A novel, possibly functional, single nucleotide polymorphism in the coding region of the thrombin-aetivatable fibrinolysis inhibitor (TAFI) gene is also associated with TAFI levels. Blood, 2001,98 : 1992-1993.
-
6Michael BB, Marlys LK. Recent advances in measurement of thrombin-activatable fibrinolysis inhibitor (TAFI) and in understanding its molecular genetics, gene regulation, and biological roles (review). Clin Biochem, 2007,40:431-442.
-
7Bjorkman JA, Abrahamsson TI, Nerme VK, etal. Inhibition of carboxypeptidase U (TAFIa) activityimproves rt-PA induced thrombolysis in a dog model of coronary artery thrombosis. Thromb Res ,2005,116:519-524.
-
8Schroeder V, Chatterjee T, Mehta H, et al. Thrombin activatable fibrinolysisinhibitor (TAFI) levels in patients with coronary artery disease investigated byangiography. Thromb Haemost, 2002,88 : 1020-1025.
-
9Segev A, Hegele RA, Lau HK, et al. Thr325Ile polymorphism of the TAFI gene is related to TAFI antigen plasma levels and angiographie restenosis after percutaneous coronary interventions. Thromb Res, 2004, 114 : 137- 141.
-
10Henry M, Aubert H, Morange PE, et al. Identification of polymorphisms in the promoter and the 3' region of the TAFI gene: evidence that plasma TAFI antigen levels are strongly genetically controlled. Blood, 2001,97 : 2053-2058.
共引文献3
-
1谢玮,刘敏涓.凝血酶激活的纤溶抑制物与糖尿病关系的研究进展[J].广州医药,2007,38(2):11-14. 被引量:12
-
2王泽筠,徐成伟,马晓丽,郑燕,郏雁飞,肖东杰,汪运山.siRNA靶向抑制CPB2基因对乳腺癌细胞TAFI表达及生长和转移的影响[J].山东大学学报(医学版),2011,49(4):57-60. 被引量:4
-
3倪萍,张斯蒙,田沛茹,时景璞.凝血酶激活的纤溶抑制剂水平与冠心病关系的Meta分析[J].中国循证心血管医学杂志,2019,11(2):155-159. 被引量:4
同被引文献61
-
1王明山,杨丽红,潘景业,王霄霞,陆红,吕美艳,陈少贤,谢于鹏.晚期肺癌患者化疗过程中抗凝血酶和纤溶功能的变化及意义[J].中国肺癌杂志,2007,10(3):226-228. 被引量:13
-
2Komurcuoglu B, Ulusoy S, Gayaf M, et al. Prognostic value of plasma D-dimer levels in lung carcinoma[J].Tumori, 2011, 97(6): 743.
-
3Zhao j, Zhao M, Jin B, et al. Tumor response and survival in patients with advanced non-small-cell lung cancer: the pre- dictive value of chemotherapy-induced changes in fibrinogen [J]. BMC Cancer, 2012, 12(1 ) : 330.
-
4Thaler J, Ay C, Pabinger I. Clinical significance of circulat- ing microparticles for venous thromboembolism in cancer pa- tients[J]. Hamostaseologie, 2012, 32(2): 127.
-
5Pangilinan J M. Venous thromboembolism in patients with cancer: an overview for pharmacists using a case-based ap- proach[J]. J Pharm Pract, 2010, 23(4):294.
-
6Battinelli E M, Murphy D L, Connors J M. Venous throm- boembolism overview [J]. Hematol Oncol Clin North Am, 2012, 26(2): 345.
-
7Kuderer N M, Ortel T L, Francis C W. Impact of venous thromboembolism and anticoagulation on cancer and cancer survival[J]. J Clin Oncol, 2009, 27(29): 4902.
-
8Sasao H, Fujiwara H, Murai H, et al. Does motor dysfunction after cerebral infarction impede the development of angina symptoms. A comparison of coronary angiographic findings in patients with and without prior cerebral infarction [J] .Int Heart J,2013,54(1) :1-6.
-
9Zhang XM, Wang WJ, Yu YL, et al.BNP and NT-proBNP assays for heart-failure diagnosis in patients with cerebral in- farction[ J] .Laboratory Medicine, 2013,44( 1 ) :46-50.
-
10Ejaz S, Williamson DJ, Ahmed T, et al. Characterizing in- farction and selective neuronal loss following temporary focal cerebral ischemia in the rat: a multi-modality imaging study [ J]. Neurobiol Dis ,2013,51 : 120-132.
引证文献6
-
1薛英波,倪婷婷,俞婕,李杭.化疗对晚期肺癌患者凝血、纤溶系统影响的临床研究[J].实用临床医药杂志,2012,16(19):46-48. 被引量:11
-
2付洪伟,李嫚.弥漫性血管内凝血评分、纤维蛋白原含量对急性脑梗死患者预后评估的价值[J].实用老年医学,2015,29(8):653-655. 被引量:5
-
3秦祥德,杨春云,张媛,倪一虹,于超,冯晓丽,徐成伟.2型糖尿病合并下肢骨折患者凝血分子标志物的变化及其与血栓形成的关系[J].山东大学学报(医学版),2015,53(11):55-58. 被引量:9
-
4朱建华.肺癌患者化疗前后凝血、纤溶功能相关指标和血小板计数变化分析[J].中国基层医药,2016,23(19):3014-3017. 被引量:4
-
5李燕.基于凝血指标的心脑血管患者预后情况判断[J].实验与检验医学,2019,37(6):1087-1089.
-
6张青,冯鷺,于超,王丽娜,徐成伟.肺癌患者血栓四项标志物检测的临床意义[J].临床检验杂志,2019,37(11):853-855. 被引量:12
二级引证文献41
-
1李政,李长树,王平,黄东红,李雳.“桃红四妙汤”对膝关节置换围手术期下肢血栓前状态干预的临床研究[J].按摩与康复医学,2019,10(1):26-28. 被引量:1
-
2董强,刘桂芹,刘建新,张艳霞,刘建军,韩克领,康国强.血府逐瘀汤加味治疗中晚期小细胞肺癌临床研究[J].河南中医,2014,34(9):1758-1760. 被引量:17
-
3刘天新.血府逐瘀胶囊对肿瘤患者血流变指标的影响研究[J].中国实用医药,2014,9(31):189-190. 被引量:3
-
4杨栋,张培彤.手术、放、化疗对恶性肿瘤患者血瘀证的影响[J].辽宁中医杂志,2015,42(1):16-18. 被引量:21
-
5赵保平,张明智,陈曦.肺癌患者化疗前后凝血、纤溶功能及血小板参数的变化及其临床意义[J].肿瘤基础与临床,2015,28(2):150-153. 被引量:12
-
6廖碧常,邹立华,李惠.血府逐瘀胶囊辅助化疗对中晚期小细胞肺癌患者疗效及凝血指标的影响[J].中国中医药信息杂志,2015,22(9):26-29. 被引量:8
-
7王亚辉.肺癌患者化疗前后凝血、纤溶功能及血小板参数变化的临床意义[J].中国综合临床,2016,32(3):263-266. 被引量:13
-
8刘悦,刘向荣.依达拉奉治疗老年短暂性脑缺血患者疗效及对血液流变学影响[J].实用老年医学,2016,30(4):326-328. 被引量:5
-
9井丽丽.依达拉奉对短暂性脑缺血发作治疗效果分析及对血液流变学影响[J].齐齐哈尔医学院学报,2016,37(21):2684-2685. 被引量:1
-
10张峰,施翔,曹真虎.创伤性四肢骨折患者凝血指标的改变与血栓形成的关系[J].中国卫生检验杂志,2017,27(6):833-835. 被引量:20
-
1秦祥德,杨春云,张媛,倪一虹,于超,冯晓丽,徐成伟.2型糖尿病合并下肢骨折患者凝血分子标志物的变化及其与血栓形成的关系[J].山东大学学报(医学版),2015,53(11):55-58. 被引量:9
-
2崔桂萍,杨萍,胡静仪,王颖,姚智.脑卒中患者血浆凝血酶激活的纤溶抑制物的临床研究[J].检验医学,2009,24(1):1-4. 被引量:4
-
3刘汉,景本年,李卓江.健康人不同年龄组血浆F_(1+2)及D-dimer检测的意义[J].临床检验杂志,2001,19(2):120-120. 被引量:1
-
4原娜,焦英华,王喆,龚欢欢,卢秀荣,张贤雨,马欢,李锦秋,张志林.凝血酶原片段1+2与宫颈癌经外周静脉穿刺中心静脉置管患者静脉血栓形成的研究[J].中国医师进修杂志,2017,40(2):111-114. 被引量:9
-
5谢爽,王鸿利,王学峰,傅启华,王文斌,周荣富,武文漫,丁秋兰,方怡,戴菁,王振义.冠心病患者血浆凝血酶激活的纤溶抑制物的检测及其临床意义[J].现代检验医学杂志,2004,19(1):42-43. 被引量:13
-
6宋娟芳,张敏华,施黎华,吴月红.胃癌患者血浆组织因子、组织因子途径抑制物的检测及其临床意义[J].检验医学,2009,24(6):412-412. 被引量:1
-
7周怡,金红.凝血酶激活的纤溶抑制物的表达与心血管疾病[J].心血管康复医学杂志,2009,18(1):81-82.
-
8董芍芍,章圣泽,叶玲丽,杨群伟,朱源.血透患者血浆TAFI与CRP相关性及临床意义[J].中国现代医生,2011,49(20):152-153. 被引量:1
-
9刘利妍,刘向群.凝血酶激活的纤溶抑制物与炎症性疾病关系的研究进展[J].国外医学(老年医学分册),2006,27(5):200-203. 被引量:2
-
10李琳,王学锋,璩斌,陈新沂.组织因子途径抑制物活性测定及其临床应用[J].上海医学检验杂志,1999,14(2):86-88. 被引量:10