摘要
目的:探讨2型糖尿病患者的血尿酸水平与肾脏早期损害指标尿白蛋白尿肌酐比(ACR)之间的关系。方法:回顾分析我院近6年来出院的150例2型糖尿病患者的临床资料。结果:发现2型糖尿病合并高尿酸血症患者的ACR的水平显著高于血尿酸水平正常的2型糖尿病患者(P<0.01),且ACR与血尿酸水平呈正相关(P<0.01)。结论:血尿酸是ACR的主要影响因素,2型糖尿病合并高尿酸血症的患者,更易出现早期肾脏损害。高尿酸在2型糖尿病患者糖尿病肾病的发生及发展中发挥重要作用,对预后有不良影响,应及时予以相关干预。
Objective：To explore the association of serum uric acid（SUA） and urine albumin-to-creatinine ratio（ACR） in patients with type 2 diabetes mellitus.Methods：Retrospective analysis was made over the clinical features of 150 patients with T2DM who were admitted in our hospital in the recent 6 years.Results：The ACR abnormal rate was higher in hyperuricemia group（P〈0.01）.ACR level was positively correlated with SUA（P〈0.01）.Conclusion：SUA was a main risk factor in ACR.Patients with hyperuricemia and type 2 diabetes mellitus were prone to develop early renal damage.Hyperuricemia is an an unfavorable prognostic factor and plays an important role in the onset and development of diabetic nephropathy among patients with T2DM.Therefore intervention should be made in time.
出处
《医学理论与实践》
2012年第9期1014-1015,1017,共3页
The Journal of Medical Theory and Practice
关键词
2型糖尿病
高尿酸血症
肾脏损害
Type 2 diabetes mellitus
Hyperuricemia
Renal damage
