摘要
目的通过对临床标本分离的36 339株病原菌进行分析,掌握住院患者常见病原菌及其耐药性,为临床合理应用抗菌药物提供依据。方法对医院2006年1月-2010年12月分离的菌株,分析其分布及抗菌药物的药敏情况。结果近5年病原菌检出中金黄色葡萄球菌在革兰阳性菌中检出率最高,占10.1%,耐甲氧西林金黄色葡萄球菌(MRSA)呈逐渐增高趋势;铜绿假单胞菌在革兰阴性菌中检出率最高,占13.4%,产ESBLs大肠埃希菌呈现增高趋势。结论检出的病原菌是医院患者常见的病原菌,MRSA及产ESBLS大肠埃希菌呈现逐渐升高,且对多种抗菌药物耐药,应引起临床高度重视。
OBJECTIVE To investigate 36 339 strains of pathogens isolated from clinical specimens,to understand the common pathogens and the drug resistance,so as to provide basis for clinical reasonable use of antibiotics.METHODS The distribution and drug susceptibility of the clinical isolates from Jan 2006 to Dec 2010 were analyzed.RESULTS In the recent five years,the detection rate of Staphyloccocus aureus was the highest（10.1%）among the gram-positive bacteria,the detection rate of methicillin-resistant Staphylococcus aureus（MRSA）kept an increasingly upward tendency;the detection rate of Pseudomonas aeruginosawas the highest（13.4%）among gram-negative bacteria,the detection rate of ESBLs-producing Escherichia coli presented as an increasing tendency.CONCLUSION The pathogens isolated from the patients are the very common in hospital,the detection rates of MRSA and ESBLs-producing E.coli strains present as an increasing tendency,those isolates are resistant to various antibiotics,which should be aroused the attention.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第9期1900-1902,共3页
Chinese Journal of Nosocomiology
关键词
病原菌
分布
耐药性
Pathogen
Distribution
Resistance
