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冠状动脉支架置入围术期应用前列地尔对C反应蛋白及支架内再狭窄的影响 被引量：6

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摘要 目的观察冠状动脉支架置入围术期应用前列地尔对C反应蛋白及术后1年内支架内再狭窄的影响。方法 97例急性冠脉综合征行冠脉支架术患者随机分为治疗组和对照组,治疗组51例,对照组46例,治疗组在抗血小板、扩血管、降脂、抗凝等治疗的基础上加用前列地尔。术后所有患者继续服用肠溶阿司匹林100 mg,氯吡格雷75mg持续1年以上。结果 2组患者C反应蛋白术后1天较术前有显著性变化(p<0.05),但与对照组比较无显著统计学意义(P>0.05),术后1周较术前均有下降,但以治疗组下降为著,2组比较差异有统计学意义(P<0.05)。于6～12个月内复查冠脉造影治疗组冠脉再狭窄率明显降低(P<0.05)。结论围术期应用前列地尔可降低冠脉支架置入术后C反应蛋白,并有效抑制炎性反应,且减少1年内支架内再狭窄的发生率。
作者 毛利荣 马涛 张瑞峰 张立欣 房体静 文军 高海明
机构地区 河北省秦皇岛市海港医院心内科 河北省秦皇岛市开发区医院内科
出处 《疑难病杂志》 CAS 2012年第5期372-374,共3页 Chinese Journal of Difficult and Complicated Cases
关键词 前列地尔 急性冠脉综合征 C反应蛋白 冠脉支架术后再狭窄
分类号 R541.4 [医药卫生—心血管疾病]
  • 相关文献

参考文献10

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二级参考文献22

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共引文献729

同被引文献41

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引证文献6

二级引证文献55

疑难病杂志
2012年 第5期

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