摘要猪种布鲁氏菌2号菌株(S2)是一株弱毒口服苗株,它具有全部猪种布鲁氏菌第1生物型(Brucella suis biovarⅠ)的特征,供预防绵羊、山羊、牛、牦牛和猪等动物布鲁氏菌病之用。从五十年代中国兽药监察所筛选出该菌株,到七十年代初期工厂化大生产和大面积使用,这期间对该菌株在实验动物、绵羊、山羊。
1Bosseray N, Plommet M. Brucella suis S2, brucella melitensis Rev. 1 and Brucella abortus S19 living vaccines: residual virulence and immunity induced against three Brucella species challenge strains in mice[ J]. Vaccine, 1990,8 (5) :462 - 468.
2Blasco JM, Matin C, Jimenez de Bagues MP, et al. Efficacy of Brucelia suis strain 2 vaccine against Brucella ovis in rams[ J]. Vaccine, 1993,11(13) :1291 -1294.
3Bosseray N,Plommet M.Brucella suis S2,brucella melitensis Rev.1and Brucella abortus S19 living vaccines:residual virulence and im-munity induced against three Brucella species challenge strains inmice[J].Vaccine,1990,8(5):462-468.
4Blasco J M,Marin C,Jiménez de Bagüés MP,et al.Efficacy of Bru-cella suis strain 2 vaccine against Brucella ovis in rams[J].Vaccine,1993,11(13):1291-1294.
