摘要
目的探讨伴代谢综合征的急性胰腺炎的临床特征。方法回顾性分析我院2007年1月至2010年12月收治的33例伴代谢综合征的急性胰腺炎患者(MetS组)的临床资料,与同期住院的35例不伴代谢综合征的急性胰腺炎(非MetS组)资料进行对比研究。结果 MetS组腹痛缓解时间(7.88±3.89)天vs(4.67±2.64)天及平均住院时间(10.60±4.86)天vs(8.11±3.77)天,较非MetS组长,复发次数较非MetS组多(2.76±1.39)次vs(1.22±0.53)次,死亡百分比高于非MetS组(3.0%vs 0);MetS组患者血钙(1.67±0.48)mmol/L vs(2.07±0.68)mmol/L、血氧分压水平(65±10)mmHg(1mmHg=0.133kPa)vs(79±12)mmHg低于非MetS组,而CRP水平高于非MetS组(156.6±17.4)mg/L vs(117.9±13.5)mg/L;MetS组中重症患者比例(30.3%vs 14.3%)、Ranson评分≥3者(33.3%vs 14.3%)、Balthazar CT分级为D、E级者(30.3%vs 11.4%)、APACHE II评分≥8分者比例(30.3%vs 14.3%)均较非MetS组高,MetS组局部及系统并发症均明显高于非MetS组(均P<0.05)。结论合并代谢综合征的急性胰腺炎通常病情较重,并发症多,易复发,积极控制代谢综合征的各个组分可能对控制胰腺炎病情及预防胰腺炎复发有利。
Objective To investigate the clinical characteristics of acute pancreatitis metabolic syndrome.Methods Sixty-eight hospitalized patients with acute pancreatitis,including 33 accompanied by metabolic syndrome（research group） and 35 without metabolic syndrome（control group） between Jan.2007 and Dec.2010 were enrolled.Results Relieved duration of abdominal pain（7.88±3.89） days vs（4.67±2.64） days and averaged hospitalized duration（10.60±4.86） days vs（8.11±3.77） days were longer in research group.Recurrence was more often in research group than in control（2.76±1.39） times vs（1.22±0.53） times.Mortality percentage was higher in research group（all P0.05）.The concentrations of Ca2＋（1.67±0.48） mmol/L vs（2.07±0.68） mmol/L and SaO2（65±10） mmHg（1 mmHg=0.133 kPa） vs（79±12） mmHg in research group were lower than those of control group but CRP was higher in former（156.6±17.4） mg/L vs（117.9±13.5） mg/L.The ratio of severe type（30.3% vs 14.3%）,Ranson grade≥3（33.3% vs 14.3%）,Balthazar CT grade D and E（30.3% vs 11.4%）,APACHE II scores≥8（30.3% vs 14.3%） in research group were higher than those of control.Local and systemic complications were higher in research group.Conclusion Patients with acute pancreatitis accompanied by metabolic syndrome often present critical status,much complications and easy relapse,active control in each component of metabolic syndrome may be useful to suppress the disease and prevent recurrence.
出处
《临床荟萃》
CAS
2012年第10期849-851,共3页
Clinical Focus
关键词
胰腺炎
急性坏死性
代谢综合征X
超声检查
pancreatitis
acute necrotizing
metabolic syndrome X
ultrasonography
