期刊文献+

73例乳腺派杰氏病临床分析 被引量:2

暂未订购
导出
摘要 目的 研究分析乳腺派杰氏(Paget′s)病的临床资料、病理特点及影响其预后的因素.方法 对哈尔滨医科大学附属第三医院1979年9月-2011年3月收治的73例病例资料完整的乳腺派杰氏病病例进行回顾性分析.结果 73例乳腺Paget′s病患者发病年龄在28~78岁之间,其中左侧42例、右侧31例.全组病人中33例接受免疫组化检查,其中29例HER2阳性.患者5年生存率为89.55%.有腋窝下淋巴结转移的Paget′s病患者发生远处转移的风险是无腋窝淋巴结转移的3.956倍(HR=3.956,95%CI:1.148-13.628).Paget′s病患者中腋窝淋巴结转移阳性患者死亡风险是阴性患者的20.666倍(HR=20.666,95%CI:2.390-178.736).结论 乳腺派杰氏病的预后较好,腋窝淋巴结转移阳性减少其无转移生存时间(MFS),同时也影响其预后生存时间.
出处 《实用肿瘤学杂志》 CAS 2012年第2期150-153,共4页 Practical Oncology Journal
  • 相关文献

参考文献11

  • 1Dixon AR, Galea MH, Ellis IO, et al. Paget's disease of the nipple [ J ]. Br J Surgery, 1991,78 ( 6 ) : 722 - 723.
  • 2Sheen Chen SM, Chen HS, Chen WJ, et al. Paget's diseaseof the breast - an easily overlooked disease [ J ] ? J Surg On- col,2001,76(4) :261 -265.
  • 3姜虹,孙先虹,马国璋.乳腺与乳腺外Paget’s病临床病理分析[J].实用肿瘤学杂志,2006,20(1):37-38. 被引量:5
  • 4Mo:rrogh M, Morris EA, Liberman L, et al. MRI identifies otherwise occult disease in select patients with paget's dis- ease of the nipple[ J], J Am Coil Surg,2008,206(2) :316 -321.
  • 5Palade R, Vasilescu D, Grigoriu M. Paget's disease of breast - a special form of breast cancer [J]. Chirurgia, 1995,d4 (4) :21 -27.
  • 6Sek P, Zawrocki A, Biernat W, et al. HER2 molecular sub- type is a dominant subtype of mammary Paget's cells. An immunohistochemical study [ J ]. Histopathology, 2010, 57 (4) ,564 -571.
  • 7Nakamura G, Shikata N, Shoji T, et al. Immunohistochemical study of mammary and extramammary Paget's disease[J].Anticancer Res, 1995,15 (2) :467 - 470.
  • 8Zakaria S, Pantvaidya G, Ghosh K, et al. Paget's disease of the breast : accuracy of preoperative assessment [ J ]. Breast Cancer Res Treat,2007,102(2) : 137 - 142.
  • 9Kim HS, Seok JH, Cha ES, et al. Significance of nipple en- hancement of Paget's disease in contrast enhanced breast MRI[J]. Arch Gynecol Obstet,2010,282 (2) : 157 - 162.
  • 10Uehara M, Yokoyama D, Kanto S, et al. A case of pagetoid carcinoma of the breast in nearly complete response by pri- mary systemic therapy [ J ]. Gan To Kagaku Ryoho, 2011, 38 ( 11 ) : 1865 - 1867.

二级参考文献15

  • 1Lloyd J,Flanagan AM.Mammary and extramammary Paget' s disease[J].J Clin Pathol,2000;53(10):742 ~ 9
  • 2Jones RE,Austin C,Ackerman AB.Extramammary Paget's disease.A critical reexamination [J].Am J Dermatopathol,1979;1(2):101 ~ 32
  • 3Sitalkin C,Ackerman AB.Mammary and extramammary Paget's disease[J].Am J Dermatopathol,1985;7(4):335~40
  • 4Desai DC,Brennan EJ,Carp NZ.Paget's disease of the male breast[J].Am Surg,1996;62(12):1068~72
  • 5Goldblum JR,Hart WR.Vulvar Paget's disease:a clinicopathologic and immunohistochemical study of 19 cases [J].Am J Surg Pathol,1997;21(10):1178 ~ 87
  • 6GoldblumJR,Hart WR.PerianalPaget's disease:ahistologicand immunohistochemical study of 11 cases with and without associated rectal adenocarcinoma [J].Am J Surg Pathol,1998;22(2):170~9
  • 7Bodnar M,Miller OF 3rd,Tyler W.Paget's disease of the male breast associated with intraductal carcinoma[J].J Am Acad Dermatol,1999,40(5):829.
  • 8Martin VG,Pellettiere EV,Gress D,et al.Paget's disease in an adolescent arising in a supernumerary nipple[J].J Cutan Pathol,1994,21(3):283.
  • 9Sahoo S,Green I,Rosen PP.Bilateral Paget disease of the nipple associated with lobular carcinoma in situ.[J]Arch Pathol Lab Med,2002,126(1):90.
  • 10Morandi L,Pession A,Marucci GL,et al.Intraepidermal cells of Paget's carcinoma of the breast can be genetically different from those of the underlying carcinoma[J].Hum Pathol,2003,34(12):1321.

共引文献13

同被引文献9

引证文献2

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部