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右美托咪定在纤维光导喉镜引导清醒气管插管中的应用 被引量：12

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摘要 目的观察右美托咪定(Dex)在纤维光导喉镜引导清醒气管插管中的镇痛、镇静效果以及对循环和呼吸功能的影响。方法困难气管插管患者40例(ASAⅠ～Ⅱ级),分为Dex组(D组,n=20)和咪达唑仑+舒芬太尼组(S组,n=20),所有患者均以1%丁卡因表面麻醉后纤维光导喉镜引导经口清醒气管插管,于用药前(T0)、用药后5 min(T1)和气管插管后即刻(T2),记录循环功能和呼吸参数应激反应的变化、镇静Ramsay评分及可能出现的不良反应等。结果所有病例均顺利完成气管内插管。两组镇静程度差异无统计学意义(P>0.05)。与T0比较,两组患者T1时HR和MAP均显著下降(P<0.05),但S组有6例(33%)注药5 min后出现以呼吸频率减慢为主的呼吸抑制。结论在表面麻醉下,采用Dex 1μg/kg静脉注射能产生有效的唤醒镇静,可以减轻困难气道处理带来的心血管反应,呼吸抑制作用低于舒芬太尼,其适合应用于保留呼吸的慢诱导气管内插管。
作者 郑耀明 瞿波 于永群 陈旭华 容颖雅 胡胜英 方锐伦
机构地区 广东省江门市人民医院麻醉科
出处 《广东医学》 CAS CSCD 北大核心 2012年第8期1070-1072,共3页 Guangdong Medical Journal
关键词 右美托咪定 纤维光导喉镜 困难气道 清醒 气管插管
分类号 R614.21 [医药卫生—麻醉学]
  • 相关文献

参考文献11

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二级参考文献15

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共引文献10

同被引文献112

  • 1金昌莲,刘环秋,何其通,冯艳华,王婧,麻海春.椎管内麻醉发生气颅和硬膜外间隙积气并发症二例[J].中华临床医师杂志（电子版）,2011,5(24):7465-7466. 被引量：7
  • 2祝祎,张宏,梁萍,于晓玲.七氟醚吸入麻醉与丙泊酚静脉麻醉在超声引导下经皮微波消融治疗肝癌中的应用[J].临床麻醉学杂志,2007,23(4):291-293. 被引量：15
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引证文献12

二级引证文献64

广东医学
2012年 第8期

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