摘要
目的 探讨脑出血患者血浆神经肽Y(NPY)的变化及其意义。方法 应用放射免疫法测定 31例脑出血患者治疗前后和 30例正常人的血浆NPY含量。结果 脑出血急性期与对照组比血浆NPY含量无显著性差异 (P >0 .0 5 ) ,经治疗在发病 1～ 2周及 3～ 4周血浆NPY含量较对照组显著升高 (P均 <0 .0 1)。结论 NPY在脑出血发病机理中可能起着重要作用。
Objectives To valuate the significance changes in plasma neuropeptide Y in hypertensive intracerebral hemorrhage.Methods Radioimmunoassay was used for detecting the plasma neuropeptide Y concentration in 31 hypertensive intracerebral hemorrhage before and after treatment,30 normal subjects.Results The plasma neuropeptide Y levels in hypertensive intracerebral hemorrhage on 1～7 th day after onset didn′t markedly change than that in normal subjects(P>0.05),the plasma neuropeptide Y in hypertensive intracerebral hemorrhage on 7～14th and 21～28th day after onset increased markedly as compared with the normal′s (P<0.01).Condusions These informations indicated that neuropeptide Y may play important role in the pathogenesis and state of hypertensive intracerebral hemorrhage.
出处
《宁夏医学杂志》
CAS
2000年第2期69-70,共2页
Ningxia Medical Journal
