摘要
目的研究乙肝后肝硬化患者消化性溃疡的临床特点,探讨小剂量心得安对肝源性溃疡愈合的影响。方法肝源性溃疡45例,观察其发病年龄、临床表现、溃疡部位、Hp感染率和并出血率及溃疡愈合率等特点。随机分为治疗组,用心得安 +泰胃美治疗;对照组,用维生素B6 +泰胃美治疗.另外选单纯性消化性溃疡22例,作为对照2组,治疗方法与对照组相同.结果肝源性溃疡发病年龄较单纯性消化性溃疡晚10年,溃疡部位以胃溃疡居多和并出血率高,.心得安可明显提高肝源性溃疡愈合率与对照组具统计学意义(P<0.05)。结论肝源性溃疡难以治愈且易并出血,门静脉高压因素可能从中发挥的作用。
Objective The clinical features of hepatogenic gastric ulcer secondary to cirrhosis from B hepatitis was observed and its management with light doses of propanolol tried.Methods 45 patients with hepatogenic ulcer were divided at random into group A ( n=23 ) treated with propanolol +tagamet and group B ( n=22 ) with vitamin B6 +tagamet . A group C of patients with peptic ulcer ( n=22 ) managed by vitamin B6 +tagamet too was enrolled as another control .Results In general hepatogenic ulcer occurred at an age of 10 years older than the peptic , with a distribution solely within stomach and a higher risk of bleeding . The use of propanolol produced significant positive effect ( P < 0.05 ) in ulcer healing . Conclusion Management with light doses of propanolol was effective for hepatogenic gastric ulcer , however it has been unlikely to respond to tranditional therapy and prone to bleed because of portal hypertension .
出处
《中华消化内镜杂志》
2000年第1期28-29,共2页
Chinese Journal of Digestive Endoscopy
