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Olig1转录因子在大鼠脊髓发育过程中的表达

Expression of the Olig1 in spinal cord of the developing rat
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摘要 目的:检测Olig1转录因子在大鼠脊髓发育过程中的表达情况。方法:选取胚胎14.5 d、18.5 d和出生后当天、出生后3 d、7 d、2周、4周及成年的大鼠脊髓,采用免疫荧光法和RT-PCR检测Olig1在脊髓的表达。结果:从胚胎14.5 d到成年大鼠的脊髓中Olig1均有表达。结论:Olig1在少突胶质细胞不同发育时期均有表达。 Objective ：To detect the expression of Oligl transcription factor in the development process of rat spinal cord. Methods： The rat spinal cord of embryonic days 14.5 and 18.5,on the day of birth,and 3 days,7 days,2 weeks and 4 weeks after birth were selected. The expression of Oligl in rat spinal cord were detected by immunofluorescence and RT-PCR. Results ： Immunofluorescence and RT-PCR showed the Oligl positive expression in spinal cord of eight group rats. Conclusions： Oligl has positive expression in different development stages of oligodendrocytes.
作者 齐琦 张玉心 赵保明 胡建国 吕合作 陈晓蓉
机构地区 安徽医科大学组织胚胎学教研室 蚌埠医学院组织移植安徽省重点实验室
出处 《蚌埠医学院学报》 CAS 2012年第4期373-375,共3页 Journal of Bengbu Medical College
基金 国家自然科学基金资助项目(81071268) 教育部科学技术研究重点项目(210103) 安徽省第五批优秀青年科技基金资助项目(10040606Y13) 安徽省教育厅自然科学研究计划项目(KJ2010B109)
关键词 脊髓 Olig1 少突胶质细胞 大鼠 spinal cord Oligl oligodendrocyte rat
分类号 R322.81 [医药卫生—人体解剖和组织胚胎学]
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参考文献12

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二级参考文献24

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蚌埠医学院学报
2012年 第4期

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