摘要
目的系统评价胰十二指肠术应用胰肠吻合术（PJ）与胰胃吻合术（PG）的临床疗效。方法计算机检索中英文数据库，对纳人的4篇随机对照试验使用RevMan5．0．18软件进行系统评价。结果纳入患者553例。Meta分析显示，PG胆瘘发生率低（0．51％，RR=0．17，P〈0．05）、腹腔积液发生率低（8．70％，RR=0．5，P〈0．01）、腹腔内多发并发症发生率低（5．70％，RR=0．26，P〈0．01），差异有统计学意义。PG组发生胃排空障碍发生率低（10．20％，RR=0．61，P〉0．05）、腹腔内并发症发生率低（29．60％，RR=0．76，P〉0．05），差异无统计学意义，但倾向于PG。两组胰瘘率、病死率差异均无统计学意义（P〉0．05）。结论在胰十二指肠切除术中应用PG是安全的，还需更多高质量的临床随机对照试验（RCT）详细论证。
Objective To provide an evidence-based perspective to panereaticojejunostomy （PJ） versus panereatieogastrostomy （PG） after pancreatieoduodenec-tomy. Methods We searched English and Chinese database. The Review Manager 5.0. 18 software was used for meta analyses and four randomized controlled trials were analyzed. Results 553 patients were included. There was significant difference between PJ and PG regarding postoperative biliary fistula （0. 51% , RR = 0. 17, P 〈 0. 05 ） , intra-abdominal fluid collection （8.70% , RR =0. 5 ,P 〈 0. 01 ）, intra-abdominal multiple complications （5.70%, RR = 0. 26 ,P 〈0. 01 ）. There was no significant difference in delayed gastric emptying （10. 20% , RR =0. 61, P 〉0. 05） and intra-abdominal complications （29. 60%, RR =0. 76 ,P 〉0. 05）. There was no significant difference in pancreatic fistula （ P 〉 0.05 ） and mortality （ P 〉 0. 05 ）. Conclusion PG after pancreati- eoduodenectomy is safe.
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
2012年第5期953-955,共3页
Chinese Journal of Experimental Surgery
