摘要
目的应用血流向量成像(VFM)技术检测慢性心力衰竭(CHF)患者收缩期左室心腔血液流场变化,初步探讨VFM技术评价CHF患者左室收缩功能的应用价值。方法选择临床明确诊断为CHF患者40例作为病例组,40例体检健康者作为对照组。在VFM成像模式下测量两组取样线上收缩期负向总流量(systole Q-,SQ-)在涡流模式下测量涡流的最大流量(Qmax)、半值面积(S)、涡流半径(r)以及涡流强度(Qmax/S),并比较两组差异。应用Simpson双平面法获取左室射血分数(LVEF),并与SO-、Qmax/S进行相关性分析。结果病例组与对照组的基底段、中间段、心尖段的SQ-均呈逐渐递减变化趋势,两组间比较差异有统计学意义(P〈0.01)。病例组收缩期Qmax及Qmax/S测值均低于对照组(P〈0.01),病例组收缩期S、r均大于对照组(P〈0.01)。Qmax/S与LVEF呈正相关(r=0.67,P〈0.01)。结论VFM技术可以定量分析CHF患者左室心腔内血流流场的变化情况,有望为临床提供一种较为准确的检测CHF患者左心室收缩功能的新方法。
Objective To approach the clinical application value of vector flow mapping (VFM) in evaluation of left ventricular systolic dysfunction in patients with chronic heart failure(CHF). Methods Forty patients with CHF were enrolled as CHF group, and forty healthy volunteers as control group. The parameters,including systole Q- (SQ-),the maximum flow volume of vortex (Qmax),the half-value area (S) ,radius of half-value area of vortex (r) and vortex intensity (Qmax/S), were measured in the VFM imaging mode and vortex mode. Difference of the parameters were evaluated between two groups. Left ventricular ejection fraction (LVEF) were derived via Simpson rule. Correlation analysis was performed between Qmax/S and LVEF. Results SQ- in both groups decreased progressively from basal segments to apical segments. Compared with control group, SQ-, Qmax and Qmax/S in CHF group were decreased (P 〈0.01) ,but S and r in CHF group were increased ( P 〈0.01). Qmax/S had a good correlation with LVEF (r=0.671, P〈0.01). Conclusions VFM technology is a new accurate way for clinical to analysis quantificationally left ventricular blood flow structure and detect the function of left ventricle in CHF patients.
出处
《中华超声影像学杂志》
CSCD
北大核心
2012年第4期281-283,共3页
Chinese Journal of Ultrasonography
基金
基金项目:教育部高等学校博士学科专项科研基金(20092307110017)
教育部高等学校博士学科点专项科研基金(20102307120012)
黑龙江省自然科学基金项目(D201078)
黑龙江省政府博士后资助基金(LRB09-361)
黑龙江省教育厅科学技术研究面上项目(11551286)