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山西汉族人群DYS578基因座遗传多态性与法医学的应用

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摘要 目的研究山西汉族人群中DYS578基因座的遗传多态性及法医学意义。方法随机抽取215例山西汉族无血缘关系男性个体静脉血1mL,EDTA抗凝,依次对其进行DNA提取,聚合酶链反应(PCR)扩增,银染显色。最后对筛选出的等位基因进行测序并按照国际法医遗传学会委员会(ISFG)推荐的原则命名各等位基因。结果山西汉族无血缘关系男性DYS578基因座观察到6、7、8、9、10,共5个等位基因。其基因变异度(GD)为0.712 5,个人识别能力(DP)和非父排除率(PE)均为0.709 2。结论 Y-STR基因座DYS578具有较高的遗传多态性,在法医学、人类遗传学和临床病理学等方面具有较高的实际应用价值。
出处 《中西医结合心脑血管病杂志》 2012年第4期500-501,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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