摘要
目的 探索复发性阿弗它溃疡 (recurrentaphthousulcer,RAU)患者淋巴细胞的姊妹染色单体互换 (sisterchromatidexchange ,SCE)频率、微核 (micronucleusrate ,MNR)发生率、染色体结构畸变率(chromosomestructuralaberrationrate ,CAR)与RAU的关系。方法 测定 6 0例RAU患者的SCE ,MNR和CAR ,应用非条件Logistic回归分析法 ,计算其致病危险度。结果 SCE、MNR和CAR均为RAU的重要致病危险因素。
Objective To study the relation of SCE, MNR, CAR of lymphocytes in RAU patients and RAU Methods SCE, MNR, CAR of 60 RAU patients were determined, and were analyzed by non condition Logistic regression and the risk ratio of the 3 studying factors was calculated Results SCE, MNR and CAR were important risk factors among many complicated causes of RAU Conclusion The results of the study showed essentially that RAU patients could have some pathological genetic predisposition and abnomal genetic materials congenitally
出处
《中华口腔医学杂志》
CAS
CSCD
北大核心
2000年第1期21-23,共3页
Chinese Journal of Stomatology
关键词
复发性
阿弗它溃疡
危险度
遗传因素
Recurrent aphthous ulcer
Genetic factor
Logistic regression
Risk ratio
