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洛伐他汀治疗不稳定型心绞痛的临床观察 被引量:1

Clinical observation of unstable angina treated by Lovastatin
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摘要 目的观察洛伐他汀治疗不稳定性心绞痛的临床疗效。方法将120例不稳定型心绞痛患者随机分为治疗组和对照组(各60例),在常规治疗的基础上,治疗组加服洛伐他汀20mg/d,2个月后比较两组的疗效、心绞痛发生情况和血脂水平。结果观察组总有效率为93.3%,显著高于对照组的76.7%(P<0.05);治疗后观察组的心绞痛发作次数和持续时间明显低于对照组,血脂代谢明显改善(P<0.05),与对照组比较差异有统计学意义(P<0.05)。结论洛伐他汀治疗不稳定性心绞痛疗效显著,安全性好,值得临床推广。 Objective To observe the clinical effect on unstable angina treated by Lovastatin.Methods 120 patients were randomly divided into test group and control group(60 each).Both groups were given conventional treatment.In addition,the test group was given 20 mg/d of Lovastatin tablets.Clinical effect of treatment was compared through a 2 months course.Results The total effectiveness of test group was 93.3%,which was significantly higher than that of the control group(76.7%;P〈0.05).Attacks of angina pectoris,duration of status anginosus and lipid metabolism were significantly improved in the test group compared with the control group(P〈0.05).Conclusion Lovastatin is an effective and safe treatment for unstable angina,and should be propagated for clinical use.
作者 张怡 杨颖
出处 《成都医学院学报》 CAS 2012年第1期103-104,158,共3页 Journal of Chengdu Medical College
关键词 洛伐他汀 不稳定型心绞痛 临床疗效 Lovastatin Unstable angina Clinical effect
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