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密度感应抑制剂及其在口腔微生物领域中的研究进展 被引量：1

Research progress on quorum sensing inhibitors in oral microbiol area
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摘要 密度感应即密度感知或群体感应,是细菌彼此间信号传递的一种机制。诸多的天然植物提取物和化合物皆具有抑制密度感应的作用。本文就革兰阴性菌的密度感应系统中N-酰基高丝氨酸内酯抑制剂和LuxS/AI-2信号系统拮抗剂及其在口腔领域中的应用作一综述。 Quorum sensing systems are bacterial cell-to-cell communication systems.Some natural substances and chemical compounds found recently interfere with quorum sensing systems.In this review we highlight inhibitors of acylhomoserine lactone and LuxS/AI-2 mediated quorum sensing in gram-negative bacteria and the corresponding research outcomes in the oral microbiol area.
作者 王爽 张利平 徐屹
机构地区 口腔疾病研究国家重点实验室四川大学 四川大学华西口腔医院牙周科
出处 《国际口腔医学杂志》 CAS 2012年第3期332-335,共4页 International Journal of Stomatology
基金 国家自然科学基金资助项目(30872872)
关键词 密度感应 抑制剂 自身诱导分子 quorum sensing inhibitor autoinducer
分类号 R780.2 [医药卫生—口腔医学]
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参考文献43

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二级参考文献26

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国际口腔医学杂志
2012年 第3期

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