摘要
目的:介绍氯胺酮(俗称K粉)滥用引发泌尿系损害的临床症状和可能的生理机制。方法:对60例氯胺酮滥用者进行临床症状观察,以及血尿常规、血生化检查和B超检查。结果:滥用人群以青少年为主,鼻吸是主要使用方式。60例氯胺酮滥用者中合并重症泌尿系症状者52例,主要临床表现为尿痛、尿急、尿频、血尿和尿失禁等下尿路刺激症状。临床症状与滥用时间和滥用剂量有关。停止氯胺酮滥用和积极的治疗,尿路刺激症状和尿失禁症状逐渐缓解或消失。但症状持续时间较长。结论:氯胺酮滥用可以导致严重的泌尿系功能损害,临床表现以下尿路刺激症状为主。停止滥用以及对症治疗可以缓解症状。B超、CT等影像学检查有助于临床诊断。
Objective：To introduce the symptom or possible physiological mechanism of urinary system damage induced by ketamin abuse. Methods：Observation was conducted on the clinical symptoms of 60 patients who abused ketamine. The patients＇ routine blood urine, blood biochemistry and type -B ultrasonic were tested. Results ： Patients administration route of absue was snorting. with katamine abuse were mainly teenagers. The maijor Among the 60 patients ,52 had severe urinary system damage The main clinical manifestations were dysuria, urinary frequency and urgency, hematuria, and urinary incontinence and other lower urinary tract irritation. The clinical symptoms were associated with the duration and dosage of katamine use. Stopping katamine abuses as well as taking positive approaches to medical treatment might have urinary irritation and urinary incontinence symptoms gradually eased or disappeared,but it might take a long time to go. Conclusion.： Ketamine abuse may cause serious urinary system damage, and lower urinary irritation is the main clinical symptom. Ketamine withdrawal and symptomatic treatment can relieve symptoms. B ultrasound, CT and other imaging studies are useful to clinical diagnosis.
出处
《中国药物依赖性杂志》
CAS
CSCD
2012年第2期122-127,共6页
Chinese Journal of Drug Dependence
关键词
氯胺酮
药物滥用
泌尿系损害
ketamine
drugs abuses
urinary system damage
