摘要
目的:探讨儿童恶性淋巴瘤的临床表现特点、诊断及治疗方法。方法:对48例小儿恶性淋巴瘤患者的临床表现、发病特点、病理分型、治疗及预后资料进行回顾性分析。结果:本组48例中男33例,女15例。年龄2～14岁,平均9.6岁,非霍奇金淋巴瘤(NHL)41例,占85.42%;霍奇金淋巴瘤(HL)7例,占14.58%;Ⅰ～Ⅱ期患儿8例,Ⅲ～Ⅳ期患儿40例;浅表淋巴结肿大为首发症状者32例;病理类型中,NHL以淋巴母细胞型最多见(占43.90%),HL以混合细胞型多见(占42.86%);NHL易发生骨髓浸润和中枢神经系统侵犯。总体治疗率低。结论:儿童恶性淋巴瘤早期临床表现具有多样性,且不典型,易误诊;预后与病期及治疗相关。
Objective：To investigate t he clinical manifestations of child hood malignant lymphoma.Methods：A retrospective study was carried out in clin ical manifestations,initial symptoms,pathological grouping,treatment and prog nosis of 48 children who hospitalized for malignant lymphoma.Results ：A tota l of 48（33 males and 15 females）childhood malignant lymphoma cases,the media age was 9.6（2～14） years,include 41（85.42%） Non-Hodgkin＇s lymphoma（NHL） and 7（14.58%） Hodgkin＇s lymphoma（HD）.Among t h ese cases,8 were stage I or Ⅱ and the rest were stage ⅡI or IV.The mose common symptoms at first was enlargement of the lymphnodes,32 of 48 cases.The general p athological type of NHL was lymphoblastic（43.90%） and mixed lymphocytic lymphoma（42.86%） in HD.Bone marrow and center nerve system involevement was common in NH L than in HD.Conclusion：The clinical manifestations of childhood malignant ly mphoma is variety and non-typical at first,it shall be attach importance to a void misdiagnosis.Prognosis relation to stage of lymphoma and treatment,it need treat for long-term.
出处
《陕西医学杂志》
CAS
2012年第1期43-44,共2页
Shaanxi Medical Journal
