摘要
目的通过对急性脑梗死患者的血尿酸水平进行测定和分析,探讨血尿酸水平与急性脑梗死预后的关系。方法收集笔者所在医院收治的经头CT和(或)MRI+DWI证实为急性脑梗死的209例患者为研究对象。所有患者均于入院次日晨抽空腹静脉血,进行血尿酸测定。采用美国国立卫生研究院卒中量表及BartheIndex指数分别于患者入院、出院时对其神经功能缺损情况及日常生活活动能力进行评定。结果与正常血尿酸组相比,高血尿酸组患者入院时、出院时的NIHSS评分及BI评分差异均有统计学意义(P<0.05)。采用Logistic回归分析显示,在校正了性别、年龄、既往病史、血糖、血脂、肌酐等因素后,高血尿酸水平仍与患者的预后呈负相关。结论急性脑梗死患者入院时血尿酸水平越高,卒中严重程度越重,预后越差。高血尿酸水平是急性脑梗死早期预后不良的危险因素,可作为估计预后的参考指标。
Objective To explore the correlation between serum uric acid levels and early-term outcome in patients with acute cerebral infarction by assaying the serum uric acid of the stroke patients. Methods We reviewed the data of 209 patients with ischemic stroke by CT or MRI＋DWI.The serum uric acid was determined as well as the score was evaluated by NIHSS and Barthe Index. Results The remarkable variations were revealed in the severity of the stroke and the ability of normal life between the high group and normal group（P 〈 0.05）.The groups were correlated with the severity of stroke. Correlation with prognosis by the Logistic regression analysis which removed the factors of sex,age,history,glucose,blood- fat and CREA. Conclusion The value of triketopurine should be the indicator to evaluate the prognosis as the risk of stroke incidence.
出处
《中国医药科学》
2012年第8期14-15,共2页
China Medicine And Pharmacy
关键词
急性脑梗死
血尿酸
预后
Acute cerebral infarction
Serum uric acid
Outcome
