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抑郁症新疗法——跨颅磁刺激 被引量：4

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摘要 跨颅磁刺激(Transcranial Magnetic Stimulation,TMS)是一种1990年代初应用于精神科临床研究的物理治疗方法。本文就跨颅磁刺激的工作原理,对抑郁症的疗效以及主要的不良反应作一简单的介绍。 1 工作原理 电与磁场是可以相互转换的,经过线圈的电流可以产生磁场,而处于磁场中的导体又可以产生电流。因此,如果把一个电磁线圈置于头皮上,快速接通与断开电容器,线圈中就会产生高强度的电流,在线圈的周围就会产生一个强有力而短暂的磁场。磁场可以穿过皮肤、软组织和颅骨。
作者 王立伟 徐筠
机构地区 上海医科大学精神医学教研室 上海市精神卫生中心
出处 《上海精神医学》 2000年第1期41-42,共2页 Shanghai Archives of Psychiatry
关键词 抑郁症 治疗 跨颅磁刺激
分类号 R749.4 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献11

  • 1[1]George M S,Lisanby S H.Transcranial magnetic stimulation.Applications in neuropsychiatry.Arch Gen Psychiatry,1999,56:300～311
  • 2[2]Hoflich G,Kasper S,Hufnager A,et al.Application of transcranial magnetic stimulation in treatment of drug-resistant major depression:a report of two cases.Hum Psychopharmacol,1993,8:361～365
  • 3[3]George M S,Wassermann E M.Rapid-rate transcranial magentic stimulation (rTMS)and ECT.Convulsive Ther,1994,10:251～253
  • 4[4]George M S.Why would you ever want to? toward understanding the antidepressant effect of rTMS.Hum Psychopharmacol,1998,13:307～313
  • 5[5]George M S,Wassermann E M,Williams W A,et al.Daily repetitive transcranial magnetic stimulation (rTMS) improves mood in depression.Neuroreport,1995,6:1853～1856
  • 6[6]Figiel G S,Epstein C,McDonald W M,et al.The use of rapid rate transcranial magnetic stimulation (rTMS) in refractory depressed patients.J Neuropsychiatry Clin Neurosci,1998,10:20～25
  • 7[7]Pascual-Leone A,Rubio B,Pallardo F,et al.Beneficial effect of rapid-rate transcranial magnetic stimulation of the left dorsolateral preforntal cortex in drug-resistant depression.Lancet,1996,348:233～237
  • 8[8]George M S,Speer A M,Molloy M,et al.Low-frequency daily left prefrontal rTMS improves mood in bipolar depression:a placebo-controlled case report.Hum Psychopharmacol,1998,13:271～275
  • 9[9]Klein E,Kreinin I,Christyakv A,et al.Therapeutic efficacy of right preforntal slow repetitive transcranial magnetic stimulation in major depression.Arch Gen Psychiatry,1999,56:315～320
  • 10[10]Nahas Z,Speer A M,Molloy M,et al.Preliminary results concerning the roles of frequency and intensity in the antidepressant effect of daily left prefrontal rTMS[abstract].Biol Psychiatry,1998,43:94

同被引文献27

  • 1孙振晓,于相芬.跨颅磁刺激治疗抑郁症的研究进展[J].国外医学（精神病学分册）,2005,32(1):43-45. 被引量：1
  • 2管宇笛.-[J].中华神经科杂志,1999,32(5):236-237.
  • 3George MS,Lisanby SH,Sackeim HA.Transcranial Magnetic stimulation.Applications in neuropsychiatry,1999,56 (4):300-311.
  • 4Berman RM,Narasimhan M,Sanacora G,et al.A randomized clinical trial of repetitive transcranial magnetic stimulation in the treatment of major depression.Biol Psychiatry,2000,47 (4):332-337.
  • 5Su TP,Huang CC,Wei IH.Add-on rTMS for medication-resistant depression:a randomized,double-blind,sham-controlled trial in Chinese patients.J Clin Psychiatry,2005,66(7):930 -937.
  • 6Isenberg K,Downs D,Pierce K,et al.Low fiequency rTMS stimulation of the right frontal cortex is as effective as high frequency rTMS stimulation of the left frontal cortex for antidepressant-flee,treatment-resistant depressed patients.Ann Clin Psychiatry,2005,17(3):153-159.
  • 7Padberg F,Zwanzger P,Keck ME,et al.Repetitive transcranial magnetic stimulation (rTMS) in major depression:relation between efficacy and stimulation intensity.Neuropsychopharmacology,2002,27 (4):638-645.
  • 8Rossini D,Lucca A,Zanardi R,et al.Transcranial magnetic stimulation in treatment -resistant depressed patients:a double -blind,placebo-controlled trial.Psychiatry Res,2005,137 (1-2):1-10.
  • 9Loo CK,Mitchell PB,Mc Farquhar TF,et al.A sham-controlled trial of the efficacy and safety of twice-daily rTMS in major depression.Psychol Med,2007,37(3):341 -349.
  • 10Anderson IM,Delvai NA,Ashim B,et al.Adjunctive fast repetitive transcranial magnetic stimulation in depression.Br J Psychiatry,2007,190:533-534.

引证文献4

二级引证文献7

上海精神医学
2000年 第1期

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