摘要
目的:观察止咳祛痰汤联合阿奇霉素治疗肺炎支原体肺炎(mycoplasmal pneumonia,MP)患儿的临床疗效。方法:将符合病例入选标准的80例MP患儿按就诊的先后顺序随机分为观察组和对照组,每组40例。对照组用阿奇霉素,观察组在对照组治疗基础上加用中药止咳祛痰汤。2组均治疗7 d为1个疗程,连续2个疗程后观察疗效。结果:观察组治愈率为82.50%,总有效率为97.50%;对照组治愈率为67.50%,总有效率为82.50%。2组治愈率、总有效率比较有明显差异(P<0.05)。观察组咳嗽、发热、肺部细湿啰音、哮喘音等临床症状消失时间短于对照组,2组比较差异有显著性(P<0.05)。X射线胸片转阴率观察组为97.50%,对照组为85.00%。2组差异比较有明显差异(P<0.05)。2组单侧病变转阴率比较无明显差异;双侧病变转阴率比较有明显差异(P<0.05)。结论:止咳祛痰汤联合阿奇霉素治疗MMP疗效显著,可较快消除咳嗽、发热、肺部细湿啰音、哮喘音等临床症状,降低白细胞,提高X射线胸片转阴率。
Objective：To study the clinical efficacy of antitussive and expectorant decoction combined with azithromycin on mycoplasma pneumoniae pneumonia（MMP）.Method： Eighty children with MP were randomly divided into azithromycin group and the group treated with azithromycin and antitussive and expectorant decoction,40 cases in each group.The therapeutic effect were observed after 2 courses（7 days for a course）of treatment.Result： In the azithromycin group,the cure rate was 82.50%,the total effective rate was 97.50%.For the combination group,67.50% and 82.50%,respectively（P0.05）.The disappeared time of cough,fever,fine rales,asthma,sound and other clinical symptoms in the azithromycin group is shorter than the combination group（P0.05）.Chest X-ray negative rate was 97.50% for the former and 85% for another（P0.05）.Bilateral lesions negative rate of the former was statistically significant compared to the later（P0.05）.Conclusion： Relieving cough and eliminating phlegm decoction combined with azithromycin had remarkable curative effect on MMP,can eliminate cough,fever,earlier fine rales,asthma,sound and other clinical symptoms,decreased white blood cell,improve X-ray negative rate.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第8期260-262,共3页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
肺炎支原体肺炎
止咳祛痰汤
阿奇霉素
mycoplasma pneumoniae pneumonia
cough expectorant soup
azithromycin
combination
