期刊文献+

降钙素原在腹腔感染中的诊断价值 被引量:23

Diagnostic value of serum procalcitonin applied in patients with abdominal infections
原文传递
导出
摘要 目的探讨血清降钙素原(PCT)对腹腔感染的诊断意义。方法选取51例确诊腹腔感染及40例确诊呼吸系统感染无并发腹腔感染的ICU患者,于确诊感染并未使用抗菌药物治疗前取血,采用酶联免疫荧光法检测血清PCT水平,采用SPSS 17.0软件进行数据分析。结果腹腔感染患者PCT阳性率为78.4%,肺部感染患者阳性率为62.5%,PCT对腹腔、呼吸系统细菌感染诊断的阳性率虽差异无统计学意义,但腹腔感染组PCT水平显著高于肺部感染组(P<0.05),而两组间血清C反应蛋白水平、白细胞计数比较差异无统计学意义。结论 PCT可有效预测腹腔感染。 OBJECTIVE To evaluate the value of serum procalcitonin in the diagnosis of abdominal infections.METHODS A total of 51 cases of patients confirmed with abdominal infections and 40 cases with single respiratory infections in ICU were selected,the blood was sampled before the diagnosis as infection and the treatment without using antibiotics,enzyme linked fluorescent assay(ELFA) was employed to measure the serum PCT.The results were statistically analyzed by using SPSS17.0.RESULTS The positive rate of PCT of the patients with abdominal infections was 78.4%,and the positive rate of the patients with pulmonary infections was 62.5%,although the difference in the positive rates of the abdominal infections and respiratory system infections diagnosed by PCT was not statistically significant,the PCT level of the patients with abdominal infection was significantly higher than those with pulmonary infections(P〈0.05),the differences in the level of serum CRP and WBC counts were not statistically significant.CONCLUSION Serum PCT level may effectively predict the abdominal infections.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2012年第8期1629-1630,共2页 Chinese Journal of Nosocomiology
关键词 降钙素原 腹腔感染 诊断 Procalcitonin Abdominal infection Diagnosis
  • 相关文献

参考文献11

  • 1Kim MH,Lim G,Kang SY. Utility of procalcitonin as an early diagnostic marker of bacteremia in patients with acute fever[J].Yonsei Medical Journal,2011,(02):566-572.
  • 2孔万权,庄荣,魏大臻,龚裕强,王征,孙来芳,陈大庆.降钙素原与血清C-反应蛋白联合测定对严重多发伤患者早期细菌感染的诊断价值[J].重庆医学,2009,38(16):2018-2019. 被引量:42
  • 3胡可,刘文恩,梁湘辉.降钙素原在细菌感染中临床应用的研究[J].中华医院感染学杂志,2011,21(1):30-33. 被引量:275
  • 4Hatzistilianou M,Rekliti A,Athanassiadou F. Procalcitonin as an early marker of bacterial infection in neutropenic febrile children with acute lymaphoblastic leukemia[J].Infamm Res,2009,(05):229-347.
  • 5Auriti C,Fiscarelli E,Ronchetti MP. Procalcitonin in detecting neonatal nosocomial sepsis[J].Archives of Disease in Childhood:Fetal and Neonatal Edition,2011,(15):151-152.
  • 6Bald C,Sungurtekin H,Gürses E. Usefulness of procalcitonin for diagnosis of sepsis in the intensive care unit[J].Critical Care,2003,(01):85-90.
  • 7Kibe S,Adams K,Barlow G. Diagnostic and prognostic biomarkers of sepsis in critical care[J].Journal of Antimicrobial Chemotherapy,2011,(66):33-40.
  • 8Meisner M,Muller V,Khakpour Z. Induction of procalcitonin and proinflammatory cytokines in an anheptic baboon endotoxin shock model[J].Shock,2003,(02):187-190.
  • 9Linscheid P,Seboek D,Nylen ES. In vitro and in vivo calcitonin I gene expression in parenchymal cells:a novel product of human adipose tissue[J].Endocrinology,2003,(12):5578-5584.
  • 10Ammori BJ,Becker KL,Kite P. Calcitonin precursors:early markers of gut barrier dysfunction in patients with acute pancreatitis[J].Pancreas,2003,(03):239-243.

二级参考文献10

  • 1Whang KT,Vath SD,Becker KL,et al.Procalcitqnin and proinflam matory cytokine interaction in sepsis[J].Shock,2000,14:73.
  • 2Benoist JF,Mimoz O,Assicot M.Procalcitonin in severe trauma[J].Ann Biol Clin,1998,56(5):571.
  • 3Casado-Flores J,Blanco-Quiros A.Procalcitonin:a new marker for bacterial infection[J].An Esp Pediatr,2001,54:69.
  • 4Preas HL,Nylen ES,Snider RH.Effects of anti-inflammatory agents on serum levels of calcitonin precursors during human experimental endotoxemia[J].J Infect Dis,2001,184:373.
  • 5Giamarellos-Boutboulis EJ,Mega A,Grecka P,et al.Procatcitonin:a marker to clearly differentiate systemic inflammatory response syndrome and sepsis in the critically ill patient[J].Intensive Care Med,2002,28:1351.
  • 6Bone RC,Balk RA,Cerra FB. ACCP/SCCM definitions for sepsis and organ failure guidelines for the use of innovative therapies in sepsis[J]. Chest, 1992,101:1644- 1655.
  • 7Joan M. The role of C reactive protein in the evaluation and management of infants with suspected sepsis[J].Adv Neonatal Care,2003,3(1):3 -13.
  • 8Povoa P, Almeida E, Moreira P,et al. C-reactive protein as an in dicator of sepsis[J]. Intensive Care Med, 2008, 24: 1052-1056.
  • 9Claeys R,Vinken S,Spapen H,etal. Plasma procalcitonin and C- reactive protein in acute septic shock: clinical and biological corerlates[J]. Crit Care Med, 2002,30(4) :757-762.
  • 10Haweky PM. Mechanisms of resistance to antibiotics[J]. In tensiev Caer Med, 2000,26 : 9 -13.

共引文献313

同被引文献220

引证文献23

二级引证文献109

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部