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皮肤神经活检在糖尿病皮肤小纤维神经病变的应用研究

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摘要 小纤维神经病为一类主要波及小直径有髓纤维(〈5μm)和无髓纤维的感觉性周围神经病。小直径纤维的损害程度极大超过大直径纤维时,称为小直径纤维感觉神经病。主要临床表现为刺痛、感觉迟钝、痛觉及温度觉降低,肢体远端多见,常见于糖尿病、淀粉样变性、营养障碍、肿瘤、药物中毒、人类免疫缺陷病毒感染、遗传性感觉神经病、莱姆病、血管炎等疾病。长期以来缺乏检查方法,此类疾病一直不被认识,近年来山于建立了皮肤神经活检免疫染色技术,确立了对小纤维感觉神经病的认识,
出处 《实用心脑肺血管病杂志》 2012年第4期701-701,共1页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
基金 江西省赣州市科技局科技计划项目课题(编号2009009)
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