摘要
目的 :探讨大剂量胸腺肽对恶性血液病化疗患者免疫功能的影响。方法 :分化疗加胸腺肽组 (用药组 )和单纯化疗组 (对照组 ) ,用药组于化疗同时每日静脉滴注胸腺肽 10 0 mg,连续 10～ 14d后检测 T淋巴细胞亚群的变化。结果 :用药组化疗后 CD3、CD4和 CD 5 6 ( NK)阳性百分率及 CD4/CD8比值均明显高于本组化疗前和对照组化疗后水平。结论
Objective:To observe the effect of large dose thymopeptides on T cell subpopulations of patients with malignant hematologic diseases under chemotherapy.Methods:We divided into two groups:chemotherapy plus thymopeptide group and simple chemotherapy group (control).The patients were given thymopeptides 100 mg/d,iv for 10~14 days.Then,we determined th changes of T cell subpopulation of their peripheral blood.Results:The positive percentages of CD 3、CD 4 and CD 56 (NK) and CD 4/CD 8 radio after chemotherapy in chemotherapy plus thymopeptide group were significantly higher than those before chemotherapy in the same group and those after chemotherapy in the other group.Conclusion:Large dose thymopeptides could increase immune function of patients with malignant hematologic diseases under chemotherapy.
出处
《临床血液学杂志》
2000年第3期112-113,共2页
Journal of Clinical Hematology
关键词
胸腺肽
恶性血液病
T淋巴细胞亚群
免疫功能
Thymopeptides Malignant hematologic diseases T lymphocyte subsets Immune function
