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血小板抗体检测和相容性血小板输注的应用 被引量:12

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摘要 血小板数量的减少或功能的缺陷都可以引起临床上的出血症状,而血小板输注是预防出血的主要手段。目前临床上普遍采用机采血小板输注,但有妊娠史的女性或多次输血的患者,易产生同种免疫,导致血小板输注无效(PTR)。本文通过对113例多次输注机采血小板的患者进行血小板抗体检测分析,探讨免疫因素在血小板输注中的作用,并试图寻找一种解决PTR的方法。
出处 《中国药物与临床》 CAS 2012年第4期494-496,共3页 Chinese Remedies & Clinics
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  • 1张洪淼,徐敏,王春香.148例输血患者HLA抗体筛查及临床应用[J].浙江预防医学,2005,17(3):69-69. 被引量:9
  • 2肖太武,侯明,李光耀,葛芙蓉,杨锡明,王景霞,栾静,赵歧刚.改良间接MAIPA法对免疫性与非免疫性血小板减少的鉴别诊断价值[J].临床血液学杂志,2006,19(2):101-102. 被引量:7
  • 3张之南.血液病诊断及疗效标准.3版.北京:科学出版社,2008.106-113.
  • 4Cines DB, Blanchette VS. Immune Thrombocytopenic Purpura. N Engl J Med,2002,28(13):995-1008.
  • 5Brighton TA,Evans S,Castaldi PA,et al. Prospective evaluation of the clinical usefulness of an antigen-specific assay (MAIPA) in idiopathic thrombocytopenic purpura and other immune thrombocytopenias. Blood, 1996,88 ( 1 ):194-201.
  • 6Stockelberg D,Hou M,Jacobsson S,et al. Detection of platelet antibodies in chronic idiopathic thrombocytopenic purpura(ITP). a comparative study using flow cytometry,a whole platelet ELISA,and an antigencapture ELISA. Eur J Haematol, 1996,56 ( 1-2):72-75.
  • 7Chong BH, Keng TB. Advances in the diagnosis of idiopathic thrombocytopenic purpura.Semin Hematol, 2000,37 (3):249-260.
  • 8Aledort LM, Hayward CP,Chen MG, et al. Prospective screening of 205 patients with ITP, including diagnosis, serological markers, and the relationship between platelet counts, endogenous thrombopoietin, and circulating antithrombopoietin antibodies. Am J Hematol,2004,76 (3):205-213.
  • 9Benson K, Fields K, Hiemenz J, et al. The platelet refractory bone marrow transplant patient: prophylaxis and treatment of bleeding. Semin Oncol, 1993,20 : 102-109.
  • 10HADDAD S A,I.ICHTIGER B,KI.EIN H G,et al. In vivo efficacy of shipped HI.A matched platelets[J]. Transfusion, 2006,46 : 1306- 1310.

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  • 1梁志伟,余仲苟,李玉巧.65例血小板输注无效患者相关因素分析[J].中国医药导报,2005,2(11):62-63. 被引量:12
  • 2刘达庄,陆萍,王健莲,包于勤,吴国光.血小板同种抗体与输血效果[J].中国输血杂志,1993,6(2):76-77. 被引量:29
  • 3陆紫敏.输注同型单采血小板有效提高再生障碍性贫血患者血小板数.同济大学学报:医学版,2008,29:103-105.
  • 4刘达庄,沈伟.血小板同种抗体与输血//刘达庄.免疫血液学.上海:上海科学技术出版社,2002:107-108.
  • 5Bajpai M,Kaura B,Marwaha N, et al. Platelet alloimmunization inmuhitransfused patients with haematologist gical disorders. NatlMed J India,2005,18(3) :134-136.
  • 6Tetsunori T. Pre-transfusion screening for platelet reactive antibod-ies. Transfuse Apher Sci,2005,33(2) :157-164.
  • 7Sensebe L Factors affecting posttransfusion platelet efficiency“close relationship between patient and product”. Trans Clin Bi-ol,2007,14(1) :90-93.
  • 8胡丽华.检验与临床诊断分析[M].北京:人民军医出版社,2009:60-62.
  • 9Bajpai M, Kaura B, Marwaha N, etal. Platelet alloimmunization inmuhi trandused patients with haematologist 81 disorders. Natl Med J India,2005,18(3) : 134-136.
  • 10Murphy M F, Metcalfe P, Ord J, et al. Disappearance of HLA and platelet specific antibodies in acute leukaemia patients alloimmu- nized by multiple transfusions. Br J Haematnl, 1987,67 (3) : 255 - 260.

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