期刊文献+

抗组胺治疗对慢性乙型肝炎患者免疫功能的影响 被引量:1

暂未订购
导出
摘要 现代医学普遍认为,慢性乙型肝炎患者病情迁延不愈与其免疫功能紊乱密切相关,而Th1/Th2平衡失调是其免疫功能紊乱的重要表现之一。近年研究发现多数慢性乙型肝炎患者存在的高组胺血症与Th1/Th2平衡失调密切相关,导致慢性乙型肝炎患者免疫功能低下[1,2]。我们选择了45例慢性中度乙型肝炎患者进行抗组胺治疗,观察其临床疗效,现报告如下。
出处 《中国药物与临床》 CAS 2012年第4期470-472,共3页 Chinese Remedies & Clinics
基金 山西省教育厅基金(01472)
  • 相关文献

参考文献10

二级参考文献44

  • 1谢华,何韶衡.组胺对肥大细胞激活的研究[J].中华微生物学和免疫学杂志,2004,24(3):168-168. 被引量:17
  • 2韩德五.肝功能衰竭发病机制的研究进展[J].中国病理生理杂志,1993,9(6):770-772. 被引量:12
  • 3田德增,别永信,任涛,朱辉,梁永杰.CpG寡脱氧核苷酶对2型糖尿病患者外周血Th1/Th2型免疫应答的调节作用[J].山西医药杂志,2006,35(6):497-499. 被引量:2
  • 4向军俭.组胺的荧光测定法的研究[J].中国医学科学院学报,1981,3(3):183-183.
  • 5Yokoyama A, Mori S, Takahashi HK, et al. Effect of amodiaquine, a histamine N methyltransferase inhibitor, on, Propionibacterium and lipopolysaccharide induced hepatitis in mice. Eur J Pharmacol, 2007, 558:179-184.
  • 6Asemissen AM, Scheibenbogen C, Letsch A, et al. Addition of histamine to interleukin 2 treatment augments type 1 T-cell responses in patients with melanoma in vivo: immunologic results from a randomized clinical trial of interleukin 2 with or without histamine (MP 104). Clin Cancer Res, 2005, 11:290-297.
  • 7Yokoyama M, Yokoyama A, Mori S, et al. Inducible histamine protects mice from P. acnes-primed and LPS- induced hepatitis through H2-receptor stimulation. Gastroenterology, 2004,127 : 892-902.
  • 8Dittmer U,Olbrich AR.Treatment of infectious diseases with immunostimulatory oligodeoxynucleotides containing CpG motifs.Curr Opin Microbiol,2003,6(5):472-477.
  • 9Senti G,Johansen P,Haug S,et al.Use of a type CpG oligodeoxynucleotides as an adjuvant in allergen-specific immunotherapy in humans:a phase Ⅰ/Ⅱa clinical trial.Clin Exp Allergy,2009,39(4):562-570.
  • 10Lai CK,Ho S,Chan CH,et al.Cytokine gene expression profile of circulating CD4+ T cells in active pulmonary tuberculosis.Chest,1997,111(3):606-611.

共引文献1853

同被引文献10

  • 1吕艳青,栗原博.组胺在机体免疫反应中的作用[J].中国药理学通报,2007,23(1):13-16. 被引量:21
  • 2Marrouche N, Grattan C. Update and insights into treatment options ibr chronic spontaneous urticaria[ J]. Expert Rev Clin Immunol, 2014, 10 (3) :397 -403.
  • 3Hamilton MJ, Horuick JL, Akin C, et al. Mast cell activation syn- drome : a newly recognized disorder with systemic clinical manifestations [J]. J Allergy Clin Immunol, 2011, 128(1) :147 -152.
  • 4Bachert C, Maurer M. Safety and efficacy of desloratadine in subjects with seasonal allergic rhinitis or chronic urticaria:Results of four post- marketing surveillance studies [ J ]. Clin Drug Investig, 2010, 30 ( 2 ) : 109 - 122.
  • 5Li N,Cao N, Niu YD, et al. Effects of the polysaccharide nucleic acid fraction of bacillus Calmette-Guerin on the production of interleukin-2 and interleukin-10 in the peripheral blood lymphocytes of patients with chronic idiopathic urticaria[J]. Biomed Rep, 2013, 1 (5) :713 -718.
  • 6Bulca S, Bayramgtirler D, Odyakmaz Demirsoy E, et al. Comparison of effects of 5 and 10 mg oral desloratadine and levocetirizine on histamine- induced wheal and flare response in healthy volunteers [ J ]. J Derma- tolog Treat, 2013 , 24(6):473-476.
  • 7Gut W, Pancer K, Abramczuk E, et al. RSV respiratory infection in children under 5 y. o. dynamics of the immune response Thl/Th2 and IgE[J]. Przegl Epidemiol, 2013, 67( 1 ) :17 -22, 105 - 109.
  • 8杨义成,肖海珍,刘镇平,吴海斌,石家宴.皮肤划痕症患者血清超氧化物歧化酶、谷胱甘肽过氧化物酶及丙二醛的检测及意义[J].岭南皮肤性病科杂志,2009,16(4):216-217. 被引量:1
  • 9惠坤,唐利,李承新.EAACI/GA2LEN/EDF/WAO荨麻疹指南:定义、分类和诊断[J].中国皮肤性病学杂志,2010,24(8):769-771. 被引量:40
  • 10何泽生,安国芝,赵海春,冯冬梅.慢性特发性荨麻疹患者外周血总IgE与C3,C4,IL-2,IL-4,IFN-γ的相关性[J].中国皮肤性病学杂志,2013,27(3):246-249. 被引量:21

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部