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CAG方案治疗老年人急性髓系白血病20例 被引量:2

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摘要 目的观察CAG方案治疗老年人急性髓系白血病(AML)的疗效及安全性。方法回顾性分析接受CAG方案治疗的老年AML患者20例的临床资料。CAG方案为阿糖胞苷10mg/m^2,每12h皮下注射,第1天至第14天;阿柔比星每天10-14mg/m^2,静脉注射,第1天至第4天;粒细胞集落刺激因子每天200μg/m^2,皮下注射,第1天至第14天。14d为1个疗程,1-2个疗程结束评价疗效,治疗1个疗程达完全缓解(CR)者用常规DA、HA、MA方案巩固治疗,连用2个疗程不缓解者则更换方案。观察治疗效果及患者不良反应。结果20例患者中18例完成治疗,其中CR5例,部分缓解(PR)7例,CR率27.8%(5/18),总有效率66.7%(12/18)。除骨髓抑制外,无严重感染、出血及重要脏器损伤。结论CAG方案治疗老年人AML疗效确切,相对安全,耐受性好。
出处 《白血病.淋巴瘤》 CAS 2012年第3期177-178,共2页 Journal of Leukemia & Lymphoma
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同被引文献21

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