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欣母沛与米索前列醇预防前置胎盘产后出血的对比研究 被引量:22

Contrast study on preventing hemorrhage after cesarean section in placenta previa by using hemabate and misoprostol.
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摘要 目的比较欣母沛与米索前列醇预防前置胎盘产后出血的临床疗效。方法选择存在产后出血高危因素并有剖宫产指征的前置胎盘孕妇60例,随机分为观察组和对照组各30例,对照组于剖宫产术中胎儿娩出后即在子宫体部注射缩宫素2U及口服米索前列醇0.4mg,观察组给予宫壁注射欣母沛250μg,两组均予20U缩宫素静脉维持。比较两组产后2h内及24h内的出血量。结果观察组产后2h内及24h内的出血量较对照组明显减少,差异有统计学意义(P<0.05)。结论应用欣母沛预防前置胎盘产后出血比米索前列醇效果更显著。 Objective To compare the clinical efficacy of hemabate and misoprostol for preventing hemorrhage after cesarean section of women with placenta previa.Methods 60 patients of cesarean section with placenta previa were assigned to two groups:observation group and control group.Control group was injected oxytocin into their uterine corpus immediately after cesarean section and oral misoprostol 0.4 mg,observation group was injected hemabate,then the two groups all were injected oxytocin by intravenous drip simultaneously.The bleeding amounts of 2 hours and 24 hours after operation were compared.Results The bleeding amounts of 2 hours and 24 hours in observation group were lower than that of the control group(P0.05).Conclusion Hemabate is more effective than misoprostol for preventing hemorrhage after cesarean section of women with placenta previa.
出处 《中国实用医药》 2012年第6期17-18,共2页 China Practical Medicine
关键词 欣母沛 米索前列醇 前置胎盘 产后出血 Hemabate Misoprostol Placenta previa Hemorrhage after cesarean section
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