摘要
目的:检测河南汉族群体14个Y-STR位点单倍型的遗传多样性,探讨其在法医物证学中的应用价值。方法:应用PCR、聚丙烯酰胺凝胶电泳、银染显带技术,分析DYS713、DYS720、DYS635、DYS456、DYS389Ⅰ、DYS390、DYS389Ⅱ、H4、DYS460(A7.1)、DYS391、DYS448、DYS393、DYS439及DYS392等14个Y-STR位点单倍型在203名河南汉族无关个体中的分布,并用于2例法医物证检案的判定。结果:203例样本中共检出203种单倍型,单倍型多样性高达1,个体识别率为0.999976。应用于2例法医物证检案,得到准确判断。结论:构建的Y-STR复合体系具有较高单倍型遗传多态性和个体识别力。
Aim：To detect 14 Y-STR loci haplotype genetic polymorphism and investigate its application value on legal physical evidence.Methods：PCR,polyacrylamide gel and silver staining banding techniques were used to detect the distribution of 14 Y-STR loci including DYS713,DYS720,DYS635,DYS456,DYS389Ⅰ,DYS390,DYS389Ⅱ,H4,DYS460（A7.1）,DYS391,DYS448,DYS393,DYS439,DYS392 in 203 unrelated individuals of Han nationality from Henan,and the result was used in 2 cases of forensic evidence.Results：A total of 203 haplotypes were detected in 203 samples,haplotype diversity value was up to 1,and individual recognition rate was 0.999 976.Used in 2 cases of forensic evidence,accurate judgement was got.Conclusion：The 14 Y-STR loci system has high haplotype diversity and discriminating power.
出处
《郑州大学学报（医学版）》
CAS
北大核心
2012年第2期223-225,共3页
Journal of Zhengzhou University(Medical Sciences)
关键词
Y-STR
单倍型
遗传多态性
河南
汉族
Y-STR
haplotype
genetic polymorphism
Henan province
Han population
