摘要
光镊是由美国科学家Arthur Ashkin于1986年发明的,是一种利用高度汇聚的激光束产生的三维梯度势阱来俘获、操纵微小粒子的技术。因其可俘获、操纵单个细胞,并在细胞和亚细胞层次上为生物医学研究提供方便,近年来,已越来越多地被应用于生物医学研究中。本文在介绍光镊的原理和特点的基础上,阐述了光镊(尤其是拉曼光镊)技术在生物医学领域中的研究进展、现状和展望。
Optical tweezers developed by Arthur Ashkin in 1986 are the technology in which a highly focalized beam of laser is utilized to form a three-dimensional gradient force trap to capture and manipulate particles in the micron-sized regime. Recently, optical tweezers have been increasingly used in the realm of biomedical research, because it can capture and manipulate single cell and facilitate the biomedical research in the cellular and sub-cellular level. In this review, the principles and characters of optical tweezers are introduced. Next, this article also presents the biomedical research progress facilitated by the technology of optical tweezers and Raman tweezers.
出处
《生物物理学报》
CAS
CSCD
北大核心
2012年第3期212-223,共12页
Acta Biophysica Sinica
关键词
光镊
拉曼光镊
生物医学
Optical tweezers
Raman tweezers
Biomedicine
