摘要
目的探讨低分子肝素钙治疗重度予痫前期的疗效及治疗期间母儿各项指标的变化。方法选取2009年6月～2011年6月在我院住院的重度子痫前期患者92例,随机分为观察组50例,对照组42例。观察两组血脂代谢水平及相关临床指标的变化。结果观察组较对照组(均经治疗后)血脂水平(血清甘油三脂TG、总胆固醇TC、低密度脂蛋白LDL-c、载脂蛋白B(apoB))有明显下降,尿量增加,尿蛋白总量减少,脐动脉血流S/D比值下降,胎儿窘迫、新生儿窒息率下降,两组产后出血量无明显差异。结论低分子肝素钙治疗重度予痫前期患者,可显著改善治疗效果;低分子肝素钙对母儿安全。
Objective：To study the effects of low-molecular-weight-heparin（LMWH） on patients with severe pre-eclampsia.Methods：A total of 92 severe pre-eclampsia patients from June 2009 to June 2011 in Hospital were divided into two groups：50 cases in the study group and 42 cases in the control group.We then observed the lipid metabolism and the clinical conditions of the two groups.Results： There was significant decrease the levels of triglyceride（TG）,total cholesterol（TC）,low density lipoprotein cholesterol（LDL-c）,apoB;but improvement in urinary volume,decrease proteinuia,umbilical blood flow,the systolic/diastolic（S/D）ratio,the rate of fetal distress and neonatal asphyxia in the study group,while there was no difference in postpartum hemorrhage between the two groups.Conclusions： LMWH has some clinical effects on severe pre-eclampsia women and it is safe for the pregnancies and their fetuses.
出处
《中国优生与遗传杂志》
2012年第4期70-72,共3页
Chinese Journal of Birth Health & Heredity
基金
福建省莆田市科技计划项目:项目编号:2011S12(2)
关键词
低分子肝素钙
重度子痫前期
血脂
Low-molecular-weight-heparin
Severe pre-eclampsia
Lipid
