摘要
恶性实体肿瘤脑膜转移发生率约5％～8％，是恶性肿瘤的致死性并发症。其临床表现不。典型，误诊率高，诊断复杂，主要依据脑脊液相关检查及神经影像学检查。尽管采用放、化疗，的多学科综合治疗，但属姑息治疗，疗效仍不理想，患者生存期极短。
Leptomeningeal metastasis （LM）, with a high omission rate in diagnosis in approximately 5 %-8 % of all patients, is increasingly recognized as a lethality complication. The diagnosis of LM remains challenges,but commonly can be established by CSF cytology or by definitive neuroimaging. Although a combination of focal radiotherapy, intrathecal chemotherapy, and systemic chemotherapy may be necessary to achieve optimal treatment of patients, but prognosis is unacceptable and therapy remains palliative in most patients.
出处
《肿瘤研究与临床》
CAS
2012年第3期208-210,共3页
Cancer Research and Clinic
关键词
脑膜
诊断
肿瘤转移
Meninges
Diagnosis
Neoplasm metastasis
