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胎儿脐动脉舒张末期血流缺失与妊娠结局的相关性研究 被引量:2

Study on the Correlation Between Absent End-diastolic Velocity in Fetal Umbilical Artery and Pregnancy Outcome
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摘要 【目的】探讨胎儿脐动脉舒张末期血流缺失(AEDV)与妊娠结局的关系。【方法】产前常规应用脉冲多普勒技术行胎儿脐动脉血流频谱检测,确诊为AEDV孕妇36例,分析AEDV与妊娠合并症、妊娠结局的关系。【结果]36例AEDV病例中,重度子痫前期69.4%(25/36),胎儿生长受限80.6%(29/36),羊水过少22.2%(8/36),妊娠期肝内胆管淤积症11.1%(4/36),妊娠期糖尿病8.3%(3/36);胎儿先天畸形发生率为16.7%(6/36),病死率55.6%(20/36)。【结论】脐动脉舒张末期血流缺失是脐动脉血流阻力增高的特有袁现,表明胎儿一胎盘循环障碍,妊娠合并症增多,胎儿预后不良,临床应给予高度重视。 [ Objective] To explore the relationship between absent end-diastolic velocity(AEDV) in the umbilical artery and the pregnancy outcome.[Methods]Pulse Doppler was used to measure fetal umbilical artery flow. A total of 36 pregnant women were diagnosed as AEDV. The correlation of AEDV with pregnancy complications and pregnancy outcomes was analyzed. [Results] Among 36 AEDV cases, there were 25 cases of severe preeclampsia(69.4 %), 29 cases of intrauterine growth retardation(IUGR) (80.6%), 8 cases of oligohydramnios(22.2%), 4 cases of interahepatic cholestasis of pregnancy(11.1%) and 3 cases of gestational diabetes mellitus(8.3%). The incident rate of fetal malformation was 16.7% (6/36) and the mortality rate was 55.6%(20/36). [Conclusion]AEDV in the umbilical artery is the unique performance of abnormally increased resistance of blood flow in the umbilical artery, which suggests fetal-placenta circulation barrier, more pregnancy complications and poor prognosis of fetus. Therefore AEDV should be paid attention.
出处 《医学临床研究》 CAS 2012年第3期423-425,共3页 Journal of Clinical Research
关键词 脐动脉 妊娠结局 Umbilical arteries pregnancy outcome
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  • 1徐红兵,曹珍修,吴味辛.脐动脉舒张末期血流缺如的胎儿血液动力学变化与围产儿结局的关系[J].中华围产医学杂志,2005,8(2):92-96. 被引量:26
  • 2Chauhan SP,Reynolds D,Cole J, et al. Absent or reversed end-diastolic flow in theumbilical artery: outcome at a community hospital[J]. J Miss State Med Assoc,2005,46 (6):163.
  • 3Malhotra N, Chanana C, Kumar S, et al. Comparison of perinatal outcome of growth-restricted fetuses with normal and abnormal umbilical artery Doppler waveforms [J]. Indian J Med Sci,2006,60(8) :311.
  • 4Yildirim G, Turhan E, Aslan H, et al. Perinatal and neonatal outcomes of growth restricted fetuses with positive end diastolic and absent or reversed umbilical artery doppler waveforms[J]. Saudi Med J, 2008,29 (3) : 403.
  • 5Arauz J F,Leon J C,Veldsquez PR,et al. Umbilical artery Doppler velocimetry and adverse perinatal outcome in severe pre-eclampsia[J]. Gynecol Obstet Mex, 2008,76 (8) :440.
  • 6Li H,Gudnason H, Olofsson P, et al. Increased uterine artery vascular impedance is related to adverse outcome of pregnancy but is present in only one-third of late thirdtrimester pre-eclamptic women [J ]. Ultrasound Obstet Gynecol,2005,25(5) :459.
  • 7Kontopoulos EV, Quintero RA, Chmait RH, et al. Percent absent end-diastolic velocity in the umbilical artery waveform as a predictor of intrauterine fetal demise of the donor twin after selective laser photocoagulation of communicating vessels in twin-twin transfusion syndrome[J]. Ultrasound Obstet Gynecol, 2007,30 (1) : 35.
  • 8Berg C, Thomsen Y, Geipel A, et al. Reversed end-diastolic flow in the umbilical artery at 10-14 weeks of gestation is associated with absent pulmonary valve syndrome [J]. Ultrasound Obstet Gyneeol,2007,30(3):254.
  • 9Figueroa DH, Hernandez AE, Acosta RR, et al. Doppler changes in the main fetal brain arteries at different stages of hemodynamic adaptation in severe intrauterine growth restriction[J]. Ultrasound Obstet Gynecol,2007,30(3):297.
  • 10Picconi JL, Hanif F, Drennan K, et al. The transitional phase of duetus venosus reversed flow in severely premature IUGR fetuses[J]. Am J Perinatol,2008,25(4) :199.

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  • 1刘艳鸽,杨秀丽.肝素治疗胎儿生长受限27例临床研究[J].中国现代应用药学,2006,23(S1):671-673. 被引量:13
  • 2苏秀莲.妊娠高血压疾病并发胎儿生长受限的防治[J].中国误诊学杂志,2006,6(13):2631-2632. 被引量:7
  • 3武秀芳,王霞.119例胎儿生长受限临床分析[J].中国优生与遗传杂志,2007,15(12):68-69. 被引量:5
  • 4陈素青.早发型重度子痫前期孕妇胎儿生长受限与IGF-1的关系[J].中外健康文摘,2011,8(14):42-43.
  • 5Damodaram M,Story L,Kulinskaya E. Early adverse perinatal complications in preterm growth-restricted fetuses [J]. Aus- tralian and New Zealand Journal of Obstetrics and Gynecology, 2011,51 (3) : 204-209.
  • 6Maulik D,Mundy D, Heitmann E. Umbilical artery Doppler in the assessment of fetal growth restriction[J]. Clinics in Perina- tology, 2011,38( 1 ) : 65-82.
  • 7Claris O,Beltrand J,Levy-Marchal C. Consequences of intrau- terine growth and early neonatal catch-up growth[J]. Seminars in Perinatology, 2010,34(3) : 207-210.
  • 8Mook KDO, Steegers EA, Eilers PH. Risk factors and outcomes associated with first-trimester fetal growth restriction[J]. Journal of the American Medical Association,2010,303(6):527-534.
  • 9Senior R, Becher H,Monaghan M. Contrast echocardiography: evi- dence-based recommendations by European Association of Echo- cardiography[J]. European Journal of Echocardiography, 2009,10 (2):194-212.
  • 10Eixarch E, Meler E, Iraola A. Neurodevelopmental outcome in 2 year old infants who were small for gestational age term fetuses with cerebral blood flow redistribution[J] Ultrasound in Obstetrics and Gynecology, 2008,32 (7) : 894-899.

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