摘要
目的比较不同浓度地佐辛复合罗哌卡因用于剖宫产术后镇痛的效果。方法选择ASAⅠ～Ⅱ级剖宫产患者60例,随机分为3组,各20例。Ⅰ组予罗哌卡因225mg;Ⅱ组予罗哌卡因225mg+地佐辛5mg;Ⅲ组予罗哌卡因225mg+地佐辛10mg。3组均用生理盐水稀释至100ml,行硬膜外术后镇痛,评价术后4、8、12、24、36h镇痛效果并记录不良反应。结果Ⅱ组和Ⅲ组镇痛效果明显优于Ⅰ组(P<0.05或P<0.01),Ⅱ组和Ⅲ组比较,差异无统计学意义。结论 0.225%罗哌卡因225mg+地佐辛5mg用于剖宫产术后硬膜外镇痛效果确切,且安全性高。
Objective To compare the effects of relieving pain of cesarean section with different concentrations of dezocine combined with ropivaeine. Methods Sixty patients with caesarean section （ ASA Ⅰ-Ⅱ ） were randomly divided into 3 groups （ n = 20）. Group Ⅰ received 225 mg ropivacine. Group Ⅱ received 225 mg ropivacine combined with 5 mg dezocine. Group Ⅲreceived 225 mg ropivacine combined with 10 mg dezocine. The medicine in the three groups was diluted to 100 ml with normal saline. The epidural analgesia was performed after operation. The analgesic effect and the adverse reaction were respectively recorded at the 4th, 8th, 12th, 24th and 36th hour after the operation. Results Group Ⅱand Group Ⅲ had a better analgesic effect than Group Ⅰ , but the effect in the two groups had no difference in statistical significance. Conclusion 0. 225% ropivacine in a dose of 225 mg combined with 5 mg dezoeine has a safety and exact effectiveness of epidural analgesia for cesarean section.
出处
《白求恩军医学院学报》
2012年第2期102-103,共2页
Journal of Bethune Military Medical College
关键词
剖宫产
硬膜外
地佐辛
罗哌卡因
Cesarean section
Epidural analgesia
Dezocine
Ropivacine
