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卵泡刺激素/黄体生成素比值与卵巢反应性的关系 被引量：7

Impact of basal FSH/LH ratio on ovarian response
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摘要 辅助生殖技术中，卵巢储备评估可以有助于预测超促排卵中的卵巢反应性。有学者认为卵泡刺激素／黄体生成素（FSH／LH）比值可以作为评估卵巢储备的指标，并与体外受精（IVF）前月经周期的长度和卵巢对FSH刺激的敏感性有关。来源于垂体的FSH和LH的分泌在正常的生殖周期中有不同的模式，它们调控卵巢生理功能的作用明显不同， Basal follicle-stimulating hormone （FSH）/luteinizing hormone （LH） ratio tends to be elevated as ovarian aging. The retrospective studies from IVF/ICSI data showed that FSH/LH ratio was associated with the ovarian response, and the proportion of poor response elevated when FSH/LH ratio 3. The elevated basal FSH/LH ratio suggested the ovarian reserve diminishing. When FSH level was within ＂normal＂ range, the elevated ratio was due to low LH concentration. Among these patients with normal FSH and low LH level, the subclinical functional hypogonadotrophic hypogonadism was related to poor ovarian response, too. An appropriate protocol is needed for a better pretreatment of subclinical, functional hypogonadotrophic hypogonadism due to ovarian aging in order to achieve a good outcome of assisted reproduction.
作者 杨冬梓 何钻玉
机构地区 中山大学孙逸仙纪念医院生殖中心
出处 《生殖医学杂志》 CAS 2012年第2期133-136,共4页 Journal of Reproductive Medicine
基金 2009年度高等学校博士学科点专项科研基金(20090171120072) 中山大学临床医学研究5010计划项目(2007017) 2010年度广东省医学科研基金(B2010088)
关键词 卵泡刺激素/黄体生成素比值 卵巢反应性 卵巢储备下降 FSH/LH ratio Ovarian response Ovarian aging
分类号 R6 [医药卫生—外科学]
  • 相关文献

参考文献13

  • 1Brodin T, Berqh T, Berqlund L,et al. Menstrual cycle length is an age-independent marker of female fertility: results from 6271 treatment cycles of in vitro fertilization [J]. Fertil Steril,2008, 90(5) : 1656-1661.
  • 2Barroso G, Oehninger S, Monzo A, et al. High FSH: LH ratio and low LH levels in basal cycle day 3: impact on follicular development and IVF outcome[J]. J Assist Reprod Genet, 2001, 18(9): 499-505.
  • 3Shrim A, Elizur SE, Seidman DS, et al. Elevated day 3 FSH/LH ratio due to low LH concentrations predicts reduced ovarian response[J/OL]. Reprod Biomed Online, 2006,12 (4):418 422.
  • 4何钻玉,李琳,陈晓莉,李予,张清学,杨冬梓.不同年龄段不孕患者控制性超排卵中卵巢低反应的预测[J].中国妇产科临床杂志,2011,12(6):410-413. 被引量：25
  • 5Sun W, Stegmann BJ, Henne M,et al. A new approach to ovarian reserve testing [J]. Fertil Steril, 2008, 90 (6): 2196-2202.
  • 6何钻玉 周冉 黄美风等.年轻患者基础FSH/LH升高及LH降低对体外受精胚胎移植控制性排卵的卵巢反应的影响.中华妇产科杂志,46(9):690-692.
  • 7Kronenbera HM, Shlomo M, Polonsky KS, et al. Williams Textbook of endocrinology [M], 11th ed. Philadelphia. Saunders Elsevier,2008 (Chapter) 24.
  • 8Bhagavath B, Carson SA. Ovulation induction in women with polycystic ovary syndrome: an update [J]. Am J Obstet Gynecol,2011 Jun 12.
  • 9Npub ahead of printl. Ulug U, Ben-Shlomo I, Tosun S, et al. The reproductive performance of women with hypogonadotropie hypogonadism in an in vitro fertilization and embryo transfer program[J]. J Assist Reprod Genet,2005,22(4) :167-171.
  • 10Kumbak B, Kahraman S. Women with hypogonadotropic hypogonadism: cycle characteristics and results of assisted reproductive techniques [J]. Aeta Obstet Gynecol Scand, 2006,85(12) :1453-1457.

二级参考文献12

  • 1Chuang CC, Chen CD, Chao KH, et al. Age is a better predictor of pregnancy potential than basal follicle stimulating hormone levels in women undergoing in vitro fertilization. Fertil Steril, 2003, 79: 63-68.
  • 2Lambalk CB, van Disseldorp J, de Koning CH, et al. Testing ovarian reserve to predict age at menopause. Maturitas, 2009, 63: 280-291.
  • 3Johnso NP, Bagrie EM, Coomarasamy A, et al. Ovarian reserve tests for predicting fertility outcomes for assisted reproductive technology: The International Systematic Collaboration of Ovarian Reserve Evaluation protocol for a systematic review of ovarian reserve test accuracy. BJOG, 2006, 113: 1472-1480.
  • 4Alviggi C, Humaidan P, Howles CM, et al. Biological versus chronological ovarian age.. implications for assisted reproductive technology. Reprod Biol Endocrinol, 2009, 7: 101.
  • 5A1-Azemi M, Killiek SR, Duffy S, et al. Multi-marker assessment of ovarian reserve predicts oocyte yield after ovulation induction. Hum Reprod, 2011, 26: 414-422.
  • 6Scott RT Jr, Hofmann GE. Prognostic assessment of ovarian reserve. FertilSteril, 1995, 63: 1-11.
  • 7Jashoman B, Mona HM, John MM. Prognostic role of ovarian reserve testing. Current Women's Health Reviews, 2010, 6: 267-272.
  • 8Scheffer GJ, Broekmans FJ, Looman CW, et al. The number of antra1 follicles in normal women with proven fertility is the best reflection of reproductive age. Hum Reprod, 2003, 18: 700-706.
  • 9Hendriks DJ, Mol BW, Bancsi LF, et al. Antral follicle count in the prediction of poor ovarian response and pregnancy after in vitro fertilization: a meta-analysis and comparison with basal follicle-stimulating hormone level. Fertll Steril, 2005, 83: 291-301.
  • 10Hendriks DJ, Kwee J, Mol BW, et al. Ultrasonography as a tool for the prediction of outcome in IVF patients: a comparative meta-analysis of ovarian volume and antral follicle count. Fertil Steril, 2007, 87: 764-775.

共引文献24

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二级引证文献57

生殖医学杂志
2012年 第2期

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