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阿托伐他汀对慢性心力衰竭患者心肾功能的影响 被引量:17

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摘要 目的探讨阿托伐他汀对慢性心力衰竭(CHF)患者心肾功能的影响。方法将100例慢性心力衰竭患者随机分为常规治疗组(n=50)和阿托伐他汀组(n=50),常规治疗组给予常规抗心力衰竭药物治疗,阿托伐他汀组在常规治疗基础上加用阿托伐他汀20mg,1次/d顿服,观察两组患者治疗3个月前后尿微量清蛋白(MAU)、高敏C反应蛋白(hs-CRP)、左室射血分数(LVEF)、左室舒张末内径(LVEDD)变化。结果 CHF患者治疗3个月后MAU、hs-CRP水平均显著降低(P<0.05),LVEF显著提高(P<0.05),LVEDD显著降低(P<0.05),但阿托伐他汀组与常规治疗组比较,MAU、hs-CRP、LVEDD水平降低更明显(P<0.05),LVEF提高更明显(P<0.05)。结论在常规治疗的基础上加用阿托伐他汀,MAU、LVEF、LVEDD水平改善更明显,提示阿托伐他汀对慢性心力衰竭患者心肾功能有保护作用。
作者 王利芳
出处 《实用心脑肺血管病杂志》 2012年第5期820-821,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
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参考文献6

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