摘要
低蛋白血症是妊娠期高血压疾病较常见的并发症之一,与大量尿蛋白的丢失或肝脏蛋白合成功能减退有关,疾病进一步发展可以引起母体严重水肿、胸腔积液、腹水、心包积液,并导致多脏器功能衰退;胎儿发生胎儿生长受限、胎儿窘迫,甚至胎死宫内,威胁母胎生命。如何合理扩容、利尿和补充白蛋白,纠正低蛋白血症是妊娠期高血压疾病治疗中的难点。文章就妊娠期高血压疾病并发低蛋白血症的发病机制、母胎影响、临床表现和治疗进行探讨。
Hypertensive disorders complicating pregnancy （HDCP） is usually complicated with hypoproteinemia, which is related to loss of proteinufia and dysfunction of liver synthesis. It will develop to a series of complications, including severe edema, ascites, hydrothorax and hydropericardium. Furthermore it will cause multiple systems dysfunction of mothers and fetal growth restriction （FGR）, fetal distress and fetal death. It threatens both mothers＇ and in- fants＇ lives. Proper fluid expansion, dieresis and protein supplement are vitally important. This article aims to review the pathogenesis, effect on mothers and infants, clinical manifestation and treatment of HDCP with hypoproteinemia.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2012年第4期256-258,共3页
Chinese Journal of Practical Gynecology and Obstetrics
关键词
妊娠期高血压疾病
低蛋白血症
扩容
利尿
hypertensive disorders complicating pregnancy
hypoproteinemia
expansion
diuretic
