摘要
目的总结运动性横纹肌溶解症的病因、临床特点、治疗及预后。方法回顾性分析2000年1月—2011年8月在唐山市工人医院确诊的17例运动性横纹肌溶解症患者的病因、临床特点、治疗及预后。结果 17例运动性横纹肌溶解症患者中同时存在感染者11例(64.7%),曾应用药物者3例(17.6%)。主要临床表现为发热、乏力、受累肌肉疼痛、肿胀、尿色改变、少尿或无尿,均有血清肌酸激酶升高。其并发症中急性肾衰竭发生率高,为58.8%。治疗包括补液、碱化尿液、减少肌肉损伤及并发症处理,必要时行肾脏替代治疗。病死率为5.9%,存活患者的肾功能恢复或维持正常。结论早期诊断并及时、正确地治疗可使存活者的肾功能恢复或维持正常。
Objective To summarize the pathogeny, clinical features, treatment methods and prognosis of exercise - induced rhabdomyolysis. Methods The pathogeny, clinical features, treatment and prognosis of 17 cases diagnosed as exercise -induced rhabdomyolysis in the Workers＇ Hospital of Tangshan from January of 2000 to August of 2011 were retrospectively ana-lysed. Results 11 out of the 17 exercise - induced rhabdomyolysis patients, accounting for 64. 7%, accompanied infection; 3, accounting for 17. 6%, had ever took medicine. In elinic the patients mainly manifested as fever, fatigue, myalgia, swell- ing of involved muscles, red urine, oliguria or anuria and high serum ereatine kinase, etc. Acute renal failure （ARF） was amajor complication, which up to 58.8% suffered. The treatment method adopted included infusing fluid, alkalizing urine, re- ducing muscle injuries, handling complications, and if necessary, using renal replacement therapy. The overall mortality rate was 5.9%, and the patients survived could have their kidney gradually restored or maintained normal renal function. ConclusionEarly diagnosis and timely and proper treatment can help the survivors restore and maintain normal renal function.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第8期915-916,共2页
Chinese General Practice
