摘要
Aim To synthesize a new water-soluble Na 2(C15H8O5)(SO3) 2 and determine its structure.Method The new water-soluble apigenin sulfonated derivative was synthesized by sulfonation with concentrated sulfuric acid at 40℃for half an hour and the products were obtained in ethanol-water(V∶V =1∶1).The structure of the product was identified by IR,NMR spectrum and elemental analysis.Results and Conclusion After highly selective introduced two - SO 3 groups at C3′and C6of the substrate,the new water-soluble apigenin sulfonated derivative,sodium 5,7,4 '-trihydroxyflavone-6,3′-sulfonate was obtained in good yield(78%) at moderate conditions.This method is an ideal synthesis way because of its simple operation,mild reaction conditions,high selectivity,easy separation of the product and higher yield.
Aim To synthesize a new water-soluble Na2C15H8O5）（SO3）2 and determine its struc- ture. Method The new water-soluble apigenin sulfonated derivative was synthesized by sulfonation with concentrated sulfuric acid at 40 ℃ for half an hour and the products were obtained in ethanol-wa- ter （ V ： V =1 ： 1）. The structure of the product was identified by IR, NMR spectrum and elementalanalysis. Results and Conclusion After highly selective introduced two --SO3 groups at C3＇ and C6 of the substrate, the new water-soluble apigenin sulfonated derivative, sodium 5, 7, 4＇-trihydroxyfla- vone-6, 3＇-sulfonate was obtained in good yield （78%） at moderate conditions. This method is an ideal synthesis way because of its simple operation, mild reaction conditions, high selectivity, easy sepa- ration of the product and higher yield.
出处
《宝鸡文理学院学报（自然科学版）》
CAS
2012年第1期10-11,共2页
Journal of Baoji University of Arts and Sciences(Natural Science Edition)
