摘要
目的比较两种主要医院感染临床标本的金黄色葡萄球菌(Staphylococcus aureus,SA)的耐药情况,为合理应用抗生素提供依据。方法收集住院患者呼吸道和伤口分泌物中的SA进行鉴定和药敏实验。结果 (1)SA分离率以伤口(46.26%)最高;呼吸道(35.97%)次之;两者之和为78.30%。(2)呼吸道和伤口的SA药物敏感性不一样。(3)呼吸道分泌物SA耐药率更高,其中MRSA(耐甲氧西林的金黄色葡萄球菌)的分离率较伤口更高。结论呼吸道和伤口是SA感染的主要部位,应加强对呼吸道和伤口的管理;临床上经验用药时,应区别对待呼吸道和伤口的SA感染。
Objective To compare the drug resistance of Staphylococcus aureus （SA） in two major kinds of clinical hospital infected specimens, and provide the basis for rational clinical use of antibiotics. Methods 368 and 433 strains of SA were isolated and identified separately from respiratory secretions （including sputum, throat swabs and scrape materials from bronchoscopy） and wound secretions of patients hospitalized in our hospital during January 2007 and December 2010 and the drug susceptibility tests of which were done simultaneously. Results （1） The SA separation rate of wound secretion was up to 46.26% which was the highest, followed by respiratory secretions which was 35.97%. But the total of both was 78.30%. （2） As to the respiratory secretions and wound exudates, the drug sensitivity of SA is not the same. （3） The drug resistance rates of SA from the specimens of respiratory secretions and its separation rate of MRSA were higher than that of wound exudates which showed significant differences by Z： test. Conclusion Respiratory tract and the wound were the major position which were infected by SA. The management of the respiratory tract and the wounds should be strengthened and during experienmental drug use, it should be treated differently as to the SA infections of the respiratory tract and the wound.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
2012年第4期298-300,共3页
Chinese Journal of Antibiotics
关键词
金黄色葡萄球菌
耐药性
呼吸道分泌物
伤口分泌物
Staphylococcus aureus
Drug resistance
Respiratory secretions
Wound secretion
