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诺和锐30治疗2型糖尿病的临床疗效观察

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摘要 目的:观察诺和锐30治疗2型糖尿病的临床疗效、依从性。方法:将60例2型糖尿病患者随机分为两组,治疗组30例用诺和锐30,对照组30例用诺和灵30R,均采用早、晚餐前两次皮下注射,诺和锐为餐前立刻注射,诺和灵30R为餐前30min注射,观察12周。分别记录空腹、餐后2h血糖、糖化血红蛋白、低血糖发生率、胰岛素用量。结果:①两组治疗后空腹血糖、餐后2h血糖及糖化血红蛋白均明显下降(P<0.01),但诺和锐30组的餐后血糖、空腹血糖下降更明显(P<0.05);②诺和锐30组低血糖发生率明显低于诺和灵30R组。结论:诺和锐30能更为平稳地降低2型糖尿病的血糖水平,尤其是餐后血糖,且安全性好,依从性好。
作者 王锁兰
机构地区 霍州市人民医院
出处 《亚太传统医药》 2012年第4期101-102,共2页 Asia-Pacific Traditional Medicine
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  • 1Basu A, Alzaid A, Dinneen S, et al. Effects of a change in the pattern of insulin delivery on carbohydrate tolerance in diabetic and nondiabetic humans in the presence of insulin resistance[J]. J Clin Invest, 1996,97:2351-2361.
  • 2Hailer H. Postprandial glucose and vascular disease[J] .Diabetic Med, 1997,14: s50-s56.
  • 3Brownlee M. Negative consequences of glycation [J]. Metabolism,2000,49(suppl 1) :9-13.
  • 4Wautier J L, Zoukourian C, Chappey O, et al. Receptor for advanced glycation end products blocks hyperpermeability in diabetic rats[J]. J Clin Invest, 1996,97:238-243.
  • 5Lindahl B, Dinesen B, Eliasson M, et al. High proinsulin concentration precedes acute myocardial infarction in a nondiabetic population[J]. Metabolism, 1999,48:1197-1202.
  • 6Jarrett R K, Kean H, McCartney P. The Whitehall study:ten year follow-up report on men with impaired glucose tolerance with reference to worsening to diabetes and predictors of death [J]. Endocrinol Metab Clin North Am, 1997,26:539-551.
  • 7Wannamethec S G, Perry I J, Shaper A G. Nonfasting serum glucose and insulin concentrations and the risk of stroke[J]. Stroke, 1999,30: 1780-1786.
  • 8Lebovitz H E. Alpha-glucosidase inhibitors[J]. Endocrinol Metab Clin North Am, 1997,26: 539-551.
  • 9The DECODE Study Group, European Diabetes Epidemiology Group. Glucose tolerance and mortality: comparison of WHO and American Diabetes Association diagnostic criteria[J].Lancet, 1999,354: 617-621.
  • 10Hanefeld M, Temelkova-kurktschiev T. The postprandial state and the risk of atherosclerosis[J]. Diabet Med, 1997,14:s6-s11.

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