摘要
目的:探讨急性脑梗死(ACI)患者治疗前后血浆ET-1和血清Hcy、IL-6水平的变化及意义。方法:应用放射免疫分析和酶联法对33例ACI患者进行了治疗前后血浆ET-1和血清Hcy、IL-6检测,并与35例正常健康人作比较。结果:ACI患者治疗前血浆ET-1和血清Hcy、IL-6水平非常显著地高于正常人组(P<0.01),经治疗2周后与正常人组比较无显著性差异(P>0.05)。结论:检测ACI患者治疗前后血浆ET-1和血清Hcy、IL-6水平的变化有助于对治疗效果和预后的监察。
Objective To explore the significance of changes of plasma ET-1 and serum Hcy, IL-6 levels after treatment in pa- tients with acute cerebral infarction. Methods Plasma ET-1 ,serum IL-6（both with RIA） and serum Hey（with ELISA） levels were measured in 33 patients with acute cerebral infarction and 35 normal controls. Results Before treatment, the plasma ET-1 and serum Hey, IL-6 levels in the patients were significantly higher than those in controls （ P 〈 0.01 ）, after treatment for 2 weeks, plasma ET-1 and serum Hey, IL-6 levels were no significant differenee（P 〉 0.05 ）. Conclusion Detection the changes of plasma ET-1 and serum Hey, IL-6 levels after treatment in patients with acute cerebral infarction might be helpful to monitor etficacy of therapy and prognosis.
出处
《放射免疫学杂志》
CAS
2012年第2期124-125,共2页
Journal of Radioimmanology
关键词
急性脑梗死内皮素-1
同型半胱氨酸白细胞介素-6
acute cerebral infarction（ ACI）, endothelin-1 （ ET-1 ） ,homocysteine（Hcy） ,interleukin-6 （IL-6）
